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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Robert Pejchal,Katie J. Doores,Laura M. Walker,Reza Khayat,Po-Ssu Huang,Shengkai Wang,Robyn L. Stanfield,Jean-Philippe Julien,Alejandra Ramos,Max Crispin,Rafael S. Depetris,Umesh Katpally,Andre J. Marozsan,Albert Cupo,Sebastien M. Maloveste,Yan Liu,Ryan McBride,Yukishige Ito,Rogier W. Sanders,Cassandra Ogohara,James C. Paulson,Ten Feizi,Christopher N. Scanlan,Chi Huey Wong,John P. Moore,William C. Olson,Andrew B. Ward,Pascal Poignard,William R. Schief,Dennis R. Burton,Ian A. Wilson

Glycan

Virology

Human immunodeficiency virus (HIV)

2011

An HIV antibody achieves potency and breadth by binding simultaneously to two conserved glycans on the viral envelope protein.

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“A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield” is a paper by Robert Pejchal Katie J. Doores Laura M. Walker Reza Khayat Po-Ssu Huang Shengkai Wang Robyn L. Stanfield Jean-Philippe Julien Alejandra Ramos Max Crispin Rafael S. Depetris Umesh Katpally Andre J. Marozsan Albert Cupo Sebastien M. Maloveste Yan Liu Ryan McBride Yukishige Ito Rogier W. Sanders Cassandra Ogohara James C. Paulson Ten Feizi Christopher N. Scanlan Chi Huey Wong John P. Moore William C. Olson Andrew B. Ward Pascal Poignard William R. Schief Dennis R. Burton Ian A. Wilson published in 2011. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.