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Tunable Thermal‐Sensitive Polymer–Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells

Hyungchul Yoon,Apoorv Shanker,Yan Wang,Molly Kozminsky,Qiao Jin,Nallasivam Palanisamy,Monika L. Burness,Ebrahim Azizi,Diane M. Simeone,Max S. Wicha,Kim J,Sunitha Nagrath

Graphene

Materials science

Circulating tumor cell

2016

A highly sensitive microfluidic system to capture circulating tumor cells from whole blood of cancer patients is presented. The device incorporates graphene oxide into a thermoresponsive polymer film to serve as the first step of an antibody functionalization chemistry. By decreasing the temperature, captured cells may be released for subsequent analysis.

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“Tunable Thermal‐Sensitive Polymer–Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells” is a paper by Hyungchul Yoon Apoorv Shanker Yan Wang Molly Kozminsky Qiao Jin Nallasivam Palanisamy Monika L. Burness Ebrahim Azizi Diane M. Simeone Max S. Wicha Kim J Sunitha Nagrath published in 2016. It has an Open Access status of “bronze”. You can read and download a PDF Full Text of this paper here.