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DOI: 10.3390/vaccines4020018
¤ OpenAccess: Gold
This work has “Gold” OA status. This means it is published in an Open Access journal that is indexed by the DOAJ.

Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems

Ru Wen,Afoma C. Umeano,Lily Francis,Nivita Divya Sharma,Smanla Tundup,Shanta Dhar

Adjuvant
Immune system
Vaccination
2016
Vaccination is one of the most popular technologies in disease prevention and eradication. It is promising to improve immunization efficiency by using vectors and/or adjuvant delivery systems. Nanoparticle (NP)-based delivery systems have attracted increasing interest due to enhancement of antigen uptake via prevention of vaccine degradation in the biological environment and the intrinsic immune-stimulatory properties of the materials. Mitochondria play paramount roles in cell life and death and are promising targets for vaccine delivery systems to effectively induce immune responses. In this review, we focus on NPs-based delivery systems with surfaces that can be manipulated by using mitochondria targeting moieties for intervention in health and disease.
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    Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems” is a paper by Ru Wen Afoma C. Umeano Lily Francis Nivita Divya Sharma Smanla Tundup Shanta Dhar published in 2016. It has an Open Access status of “gold”. You can read and download a PDF Full Text of this paper here.