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Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45 /glycophorin-A-bone marrow cells

Andrew C.W. Zannettino,Sharon Paton,Angela Kortesidis,Fiona Khor,Silviu Itescu,Stan Gronthos

CD34

Stromal cell

Glycophorin

2007

Magnetic and flow cytometry-based methods were used to characterize clonogenic stromal cells in human bone marrow. STRO-1(bright) stromal cells were found to lack expression of CD34, CD45 and glycophorin-A markers associated with hematopoietic progenitor cells. These studies support the view that these are two distinct stem cell compartments in adult bone marrow.

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“Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45 /glycophorin-A-bone marrow cells” is a paper by Andrew C.W. Zannettino Sharon Paton Angela Kortesidis Fiona Khor Silviu Itescu Stan Gronthos published in 2007. It has an Open Access status of “gold”. You can read and download a PDF Full Text of this paper here.