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Supplementary Figure S4 from Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma

Adrián Mariño‐Enríquez,Jan Philipp Novotný,Doga Gulhan,Isabella Klooster,Antuan V. Tran,Macy Kasbo,Meijun Z. Lundberg,Wen‐Bin Ou,Derrick L. Tao,Daniel F. Pilco‐Janeta,Victor Y. Mao,Frank T. Zenke,Brittaney A. Leeper,Prafulla C. Gokhale,Glenn S. Cowley,Laurence H. Baker,Karla V. Ballman,David E. Root,Joachim Albers,Peter J. Park,Suzanne George,Jonathan A. Fletcher

Gene knockdown

Doxorubicin

Puromycin

2023

<p>Supplementary Figure S4: PRKDC and RPA2 are essential for LMS cells, as demonstrated by cell morphology after shRNAmediated knockdown under puromycin selection at day 7 in LMS04 and LMS05 cells (quantification is provided in Figure 2C).</p>

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“Supplementary Figure S4 from Hyper-Dependence on NHEJ Enables Synergy between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma” is a paper by Adrián Mariño‐Enríquez Jan Philipp Novotný Doga Gulhan Isabella Klooster Antuan V. Tran Macy Kasbo Meijun Z. Lundberg Wen‐Bin Ou Derrick L. Tao Daniel F. Pilco‐Janeta Victor Y. Mao Frank T. Zenke Brittaney A. Leeper Prafulla C. Gokhale Glenn S. Cowley Laurence H. Baker Karla V. Ballman David E. Root Joachim Albers Peter J. Park Suzanne George Jonathan A. Fletcher published in 2023. It has an Open Access status of “bronze”. You can read and download a PDF Full Text of this paper here.