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Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo

Susan Ashton,Young Ho Song,Jim Nolan,Elaine Cadogan,Jim Murray,Rajesh Odedra,John R. Foster,Peter A. Hall,Susan C. Low,Paula Taylor,Rebecca Ellston,Urszula M. Polanska,Joanne Wilson,Colin Howes,Aaron Smith,Richard J. A. Goodwin,John G. Swales,Nicole Strittmatter,Zoltán Takáts,Anna Nilsson,Per E. Andrén,Dawn Trueman,Mike Walker,Corinne Reimer,Greg Troiano,Donald M. Parsons,David De Witt,Marianne Ashford,Jeff Hrkach,Stephen E. Zale,Philip J. Jewsbury,Simon T. Barry

In vivo

Cancer research

Kinase

2016

A nanoparticle formulation of an Aurora B kinase inhibitor uses ion pairing to achieve controlled release and efficacious, nontoxic target inhibition in tumors.

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“Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo” is a paper by Susan Ashton Young Ho Song Jim Nolan Elaine Cadogan Jim Murray Rajesh Odedra John R. Foster Peter A. Hall Susan C. Low Paula Taylor Rebecca Ellston Urszula M. Polanska Joanne Wilson Colin Howes Aaron Smith Richard J. A. Goodwin John G. Swales Nicole Strittmatter Zoltán Takáts Anna Nilsson Per E. Andrén Dawn Trueman Mike Walker Corinne Reimer Greg Troiano Donald M. Parsons David De Witt Marianne Ashford Jeff Hrkach Stephen E. Zale Philip J. Jewsbury Simon T. Barry published in 2016. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.