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DOI: 10.1126/science.7604262
OpenAccess: Closed
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Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals
Laurence G. Rahme,Emily Stevens,Sean F. Wolfort,Jing Shao,Ronald G. Tompkins,Frederick M. Ausubel
Virulence
Ecotype
Biology
1995
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model. UCBPP-PA14 exhibits ecotype specificity for Arabidopsis , causing a range of symptoms from none to severe in four different ecotypes. In the mouse model, UCBPP-PA14 is as lethal as other well-studied P. aeruginosa strains. Mutations in the UCBPP-PA14 toxA , plcS , and gacA genes resulted in a significant reduction in pathogenicity in both hosts, indicating that these genes encode virulence factors required for the full expression of pathogenicity in both plants and animals.
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“Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals” is a paper by Laurence G. Rahme Emily Stevens Sean F. Wolfort Jing Shao Ronald G. Tompkins Frederick M. Ausubel published in 1995. It has an Open Access status of “closed”. You can read and download a PDF Full Text of this paper here.