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Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in <i>NOTCH1</i>

Nishant Agrawal,Mitchell J. Frederick,Curtis R. Pickering,Chetan Bettegowda,Kyle Chang,Ryan J. Li,Carole Fakhry,Tianyi Xie,Jiexin Zhang,Jing Wang,Nianxiang Zhang,Adel K. El‐Naggar,Samar A. Jasser,John N. Weinstein,Lisa R. Treviño,Jennifer Drummond,Donna M. Muzny,Yuanqing Wu,Laura D. Wood,Ralph H. Hruban,William H. Westra,Wayne M. Koch,Joseph A. Califano,Richard A. Gibbs,David Sidransky,Bert Vogelstein,Victor E. Velculescu,Nickolas Papadopoulos,David A. Wheeler,Kenneth W. Kinzler,Jeffrey N. Myers

Exome sequencing

Head and neck

Exome

2011

The mutational profile of head and neck cancer is complex and may pose challenges to the development of targeted therapies.

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“Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in <i>NOTCH1</i>” is a paper by Nishant Agrawal Mitchell J. Frederick Curtis R. Pickering Chetan Bettegowda Kyle Chang Ryan J. Li Carole Fakhry Tianyi Xie Jiexin Zhang Jing Wang Nianxiang Zhang Adel K. El‐Naggar Samar A. Jasser John N. Weinstein Lisa R. Treviño Jennifer Drummond Donna M. Muzny Yuanqing Wu Laura D. Wood Ralph H. Hruban William H. Westra Wayne M. Koch Joseph A. Califano Richard A. Gibbs David Sidransky Bert Vogelstein Victor E. Velculescu Nickolas Papadopoulos David A. Wheeler Kenneth W. Kinzler Jeffrey N. Myers published in 2011. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.