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Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions

Jan Schuemann,Alexander F. Bagley,R. Berbeco,Kyle Bromma,Karl T. Butterworth,Hilary L. Byrne,Devika B. Chithrani,Sang Hyun Cho,Jason R. Cook,Vincent Favaudon,Yaser Hadi Gholami,E. Gargioni,James F. Hainfeld,Félicien Hespeels,Anne-Catherine Heuskin,Udoka Ibeh,Zdenka Kuncic,Sijumon Kunjachan,S. Lacombe,Stéphane Lucas,François Lux,S. J. McMahon,Dmitry Nevozhay,Wilfred Ngwa,J. Donald Payne,Sébastien Penninckx,Erika Porcel,Kevin M. Prise,Hans Rabus,Sharif M Ridwan,Benedikt Rudek,Léon Sanche,Bijay Singh,Henry M. Smilowitz,Konstantin V. Sokolov,Srinivas Sridhar,Yaroslav Stanishevskiy,Wonmo Sung,Olivier Tillement,Needa Virani,Wassana Yantasee,Sunil Krishnan

Nanotechnology

Medical physics

Radiation therapy

2020

This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z = 22, to Bismuth, Z = 83) and a similarly wide spectrum of potential clinical applications, including diagnostic, therapeutic (radiation dose enhancers, hyperthermia inducers, drug delivery vehicles, vaccine adjuvants, photosensitizers, enhancers of immunotherapy) and theranostic (combining both diagnostic and therapeutic), are being fabricated and evaluated. This roadmap covers contributions from experts in these topics summarizing their view of the current status and challenges, as well as expected advancements in technology to address these challenges.

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“Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions” is a paper by Jan Schuemann Alexander F. Bagley R. Berbeco Kyle Bromma Karl T. Butterworth Hilary L. Byrne Devika B. Chithrani Sang Hyun Cho Jason R. Cook Vincent Favaudon Yaser Hadi Gholami E. Gargioni James F. Hainfeld Félicien Hespeels Anne-Catherine Heuskin Udoka Ibeh Zdenka Kuncic Sijumon Kunjachan S. Lacombe Stéphane Lucas François Lux S. J. McMahon Dmitry Nevozhay Wilfred Ngwa J. Donald Payne Sébastien Penninckx Erika Porcel Kevin M. Prise Hans Rabus Sharif M Ridwan Benedikt Rudek Léon Sanche Bijay Singh Henry M. Smilowitz Konstantin V. Sokolov Srinivas Sridhar Yaroslav Stanishevskiy Wonmo Sung Olivier Tillement Needa Virani Wassana Yantasee Sunil Krishnan published in 2020. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.