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pH-Responsive and near-infrared-emissive polymer nanoparticles for simultaneous delivery, release, and fluorescence tracking of doxorubicin in vivo

Jicheng Yu,Yulei Chen,Yuqi Zhang,Xikuang Yao,Chenggen Qian,Jun Huang,Sha Zhu,Xiqun Jiang,Qun Shen,Zhen Gu

Doxorubicin

Conjugated system

Dextran

2014

Dextran modified with pendant acetals is used to load doxorubicin (DOX) and a near-infrared-emissive conjugated polymer (BTTPF), and this aims to provide selective drug release at therapeutic targets including tumors. The BTTPF is applicable to tracking the anticancer drug release through the change of Förster resonance energy transfer efficiency between doxorubicin and BTTPF during degradation of the nanoparticles in vivo.

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“pH-Responsive and near-infrared-emissive polymer nanoparticles for simultaneous delivery, release, and fluorescence tracking of doxorubicin in vivo” is a paper by Jicheng Yu Yulei Chen Yuqi Zhang Xikuang Yao Chenggen Qian Jun Huang Sha Zhu Xiqun Jiang Qun Shen Zhen Gu published in 2014. It has an Open Access status of “closed”. You can read and download a PDF Full Text of this paper here.