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DOI: 10.1039/b306682g
OpenAccess: Closed
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Effects of β-sheet breaker peptide polymers on scrapie-infected mouse neuroblastoma cells and their affinities to prion protein fragment PrP(81–145)

Takehisa Oishi,Kiyokazu Hagiwara,Tomoya Kinumi,Yoshio Yamakawa,Masahiro Nishijima,Kazuhiko Nakamura,Hirokazu Arimoto

Chemistry
Peptide
Scrapie
2003
The effects of Soto's 'beta-sheet breaker peptide' and its polymer on PrPSc formation in ScN2a cells were investigated. Surface plasmon resonance study indicated that direct binding between PrP(81-145) and the 'beta-sheet breaker peptide' is not specific and may not play a major role in the inhibition of PrPSc formation.
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    Effects of β-sheet breaker peptide polymers on scrapie-infected mouse neuroblastoma cells and their affinities to prion protein fragment PrP(81–145)” is a paper by Takehisa Oishi Kiyokazu Hagiwara Tomoya Kinumi Yoshio Yamakawa Masahiro Nishijima Kazuhiko Nakamura Hirokazu Arimoto published in 2003. It has an Open Access status of “closed”. You can read and download a PDF Full Text of this paper here.