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DOI: 10.1038/nrm1618
¤ OpenAccess: Green
This work has “Green” OA status. This means it may cost money to access on the publisher landing page, but there is a free copy in an OA repository.
Translational control in stress and apoptosis
Martin Holčı́k,Nahum Sonenberg
Internal ribosome entry site
Translation (biology)
Translational regulation
2005
Cells respond to stress stimuli through coordinated changes in gene expression. The regulation of translation is often used under these circumstances because it allows immediate and selective changes in protein levels. There are many examples of translational control in response to stress. Here we examine two representative models, the regulation of eukaryotic initiation factor-2alpha by phosphorylation and internal ribosome initiation through the internal ribosome-entry site, which illustrate the importance of translational control in the cellular stress response and apoptosis.
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“Translational control in stress and apoptosis” is a paper by Martin Holčı́k Nahum Sonenberg published in 2005. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.