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The oyster genome reveals stress adaptation and complexity of shell formation

Guofan Zhang,Xiaodong Fang,Ximing Guo,Li Li,Ruibang Luo,Fei Xu,Pengcheng Yang,Linlin Zhang,Xiaotong Wang,Hongsheng Qi,Zhiqiang Xiong,Huayong Que,Yinlong Xie,Peter W.H. Holland,Jordi Paps,Yabing Zhu,Fucun Wu,Yuanxin Chen,Jiafeng Wang,Chunfang Peng,Jie Meng,Ling Yang,Jun Li,Bo Wen,Na Zhang,Zhiyong Huang,Qihui Zhu,Yue Feng,Andrew S. Mount,Dennis Hedgecock,Zhe Xu,Yunjie Liu,Tomislav Domazet‐Lošo,Yishuai Du,Xiaoqing Sun,Shoudu Zhang,Binghang Liu,Peizhou Cheng,Xuanting Jiang,Juan Li,Dingding Fan,Wei Wang,Wenjing Fu,Tong Wang,Bo Wang,Jibiao Zhang,Zhiyu Peng,Yingxiang Li,Na Li,Jinpeng Wang,Maoshan Chen,Yan He,Fengji Tan,Xiaorui Song,Qiumei Zheng,Ronglian Huang,Hailong Yang,Xuedi Du,Li Chen,Mei Yang,Patrick M. Gaffney,Shan Wang,Longhai Luo,Zhicai She,Ming Yao,Wen Huang,Shu Zhang,Baoyu Huang,Yong Zhang,Tao Qu,Peixiang Ni,Guoying Miao,Junyi Wang,Qiang Wang,Christian E. W. Steinberg,Haiyan Wang,Ning Li,Lumin Qian,Guojie Zhang,Yingrui Li,Huanming Yang,Xiao Liu,Jian Wang,Ye Yin,Jun Wang

Biology

Oyster

Pacific oyster

2012

The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set of genes responding to environmental stress. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster's adaptation to sessile life in the highly stressful intertidal zone. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa.

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“The oyster genome reveals stress adaptation and complexity of shell formation” is a paper by Guofan Zhang Xiaodong Fang Ximing Guo Li Li Ruibang Luo Fei Xu Pengcheng Yang Linlin Zhang Xiaotong Wang Hongsheng Qi Zhiqiang Xiong Huayong Que Yinlong Xie Peter W.H. Holland Jordi Paps Yabing Zhu Fucun Wu Yuanxin Chen Jiafeng Wang Chunfang Peng Jie Meng Ling Yang Jun Li Bo Wen Na Zhang Zhiyong Huang Qihui Zhu Yue Feng Andrew S. Mount Dennis Hedgecock Zhe Xu Yunjie Liu Tomislav Domazet‐Lošo Yishuai Du Xiaoqing Sun Shoudu Zhang Binghang Liu Peizhou Cheng Xuanting Jiang Juan Li Dingding Fan Wei Wang Wenjing Fu Tong Wang Bo Wang Jibiao Zhang Zhiyu Peng Yingxiang Li Na Li Jinpeng Wang Maoshan Chen Yan He Fengji Tan Xiaorui Song Qiumei Zheng Ronglian Huang Hailong Yang Xuedi Du Li Chen Mei Yang Patrick M. Gaffney Shan Wang Longhai Luo Zhicai She Ming Yao Wen Huang Shu Zhang Baoyu Huang Yong Zhang Tao Qu Peixiang Ni Guoying Miao Junyi Wang Qiang Wang Christian E. W. Steinberg Haiyan Wang Ning Li Lumin Qian Guojie Zhang Yingrui Li Huanming Yang Xiao Liu Jian Wang Ye Yin Jun Wang published in 2012. It has an Open Access status of “hybrid”. You can read and download a PDF Full Text of this paper here.