DOI: 10.1038/nature03025

¤ OpenAccess: Bronze

This work has “Bronze” OA status. This means it is free to read on the publisher landing page, but without any identifiable license.

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

Olivier Jaillon,Jean‐Marc Aury,Frédéric Brunet,Jean-Louis Petit,Nicole Stange-Thomann,Evan Mauceli,Laurence Bouneau,Cécile Fischer,Catherine Ozouf−Costaz,Alain Bernot,Sophie Nicaud,David B. Jaffe,Sheila Fisher,Georges Lutfalla,Carole Dossat,Béatrice Segurens,Corinne Dasilva,Marcel Salanoubat,Michael A. Levy,Nathalie Boudet,Sergi Castellano,Véronique Anthouard,Claire Jubin,Vanina Castelli,Michaël Katinka,Benoît Vacherie,Christian Biémont,Zineb Skalli,Laurence Cattolico,Julie Poulain,Véronique de Berardinis,Corinne Cruaud,Simone Duprat,Philippe Brottier,Jean-Pierre Coutanceau,Jérôme Gouzy,Genı́s Parra,Guillaume Lardier,Charles E. Chapple,Kevin McKernan,Paul McEwan,Stephanie Bosak,M Kellis,Jean‐Nicolas Volff,Roderic Guigó,Michael C. Zody,Jill P. Mesirov,Kerstin Lindblad‐Toh,Bruce W. Birren,Chad Nusbaum,Daniel Kahn,Marc Robinson‐Rechavi,Vincent Laudet,Vincent Schächter,Françis Quétier,William Saurin,Claude Scarpelli,Patrick Wincker,Eric S. Lander,Jean Weissenbach,Hugues Roest Crollius

Genome

Biology

Vertebrate

2004

Tetraodon nigroviridis is a freshwater puffer fish with the smallest known vertebrate genome. Here, we report a draft genome sequence with long-range linkage and substantial anchoring to the 21 Tetraodon chromosomes. Genome analysis provides a greatly improved fish gene catalogue, including identifying key genes previously thought to be absent in fish. Comparison with other vertebrates and a urochordate indicates that fish proteins have diverged markedly faster than their mammalian homologues. Comparison with the human genome suggests approximately 900 previously unannotated human genes. Analysis of the Tetraodon and human genomes shows that whole-genome duplication occurred in the teleost fish lineage, subsequent to its divergence from mammals. The analysis also makes it possible to infer the basic structure of the ancestral bony vertebrate genome, which was composed of 12 chromosomes, and to reconstruct much of the evolutionary history of ancient and recent chromosome rearrangements leading to the modern human karyotype.

Cite this:

Generate Citation

“Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype” is a paper by Olivier Jaillon Jean‐Marc Aury Frédéric Brunet Jean-Louis Petit Nicole Stange-Thomann Evan Mauceli Laurence Bouneau Cécile Fischer Catherine Ozouf−Costaz Alain Bernot Sophie Nicaud David B. Jaffe Sheila Fisher Georges Lutfalla Carole Dossat Béatrice Segurens Corinne Dasilva Marcel Salanoubat Michael A. Levy Nathalie Boudet Sergi Castellano Véronique Anthouard Claire Jubin Vanina Castelli Michaël Katinka Benoît Vacherie Christian Biémont Zineb Skalli Laurence Cattolico Julie Poulain Véronique de Berardinis Corinne Cruaud Simone Duprat Philippe Brottier Jean-Pierre Coutanceau Jérôme Gouzy Genı́s Parra Guillaume Lardier Charles E. Chapple Kevin McKernan Paul McEwan Stephanie Bosak M Kellis Jean‐Nicolas Volff Roderic Guigó Michael C. Zody Jill P. Mesirov Kerstin Lindblad‐Toh Bruce W. Birren Chad Nusbaum Daniel Kahn Marc Robinson‐Rechavi Vincent Laudet Vincent Schächter Françis Quétier William Saurin Claude Scarpelli Patrick Wincker Eric S. Lander Jean Weissenbach Hugues Roest Crollius published in 2004. It has an Open Access status of “bronze”. You can read and download a PDF Full Text of this paper here.