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DOI: 10.1016/j.cmet.2011.08.016
¤ OpenAccess: Hybrid
This work has “Hybrid” OA status. This means it is free under an open license in a toll-access journal.
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
Marcel Bélanger,Igor Allaman,Pierre J. Magistretti
Neuroscience
Astrocyte
Energy metabolism
2011
The energy requirements of the brain are very high, and tight regulatory mechanisms operate to ensure adequate spatial and temporal delivery of energy substrates in register with neuronal activity. Astrocytes-a type of glial cell-have emerged as active players in brain energy delivery, production, utilization, and storage. Our understanding of neuroenergetics is rapidly evolving from a "neurocentric" view to a more integrated picture involving an intense cooperativity between astrocytes and neurons. This review focuses on the cellular aspects of brain energy metabolism, with a particular emphasis on the metabolic interactions between neurons and astrocytes.
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“Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation” is a paper by Marcel Bélanger Igor Allaman Pierre J. Magistretti published in 2011. It has an Open Access status of “hybrid”. You can read and download a PDF Full Text of this paper here.