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DOI: 10.1016/j.cell.2010.09.031
¤ OpenAccess: Hybrid
This work has “Hybrid” OA status. This means it is free under an open license in a toll-access journal.
Biological Applications of Protein Splicing
Miquel Vila-Perelló,Tom W. Muir
Intein
Protein splicing
Biology
2010
Protein splicing is a naturally occurring process in which a protein editor, called an intein, performs a molecular disappearing act by cutting itself out of a host protein in a traceless manner. In the two decades since its discovery, protein splicing has been harnessed for the development of several protein-engineering methods. Collectively, these technologies help bridge the fields of chemistry and biology, allowing hitherto impossible manipulations of protein covalent structure. These tools and their application are the subject of this Primer.
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“Biological Applications of Protein Splicing” is a paper by Miquel Vila-Perelló Tom W. Muir published in 2010. It has an Open Access status of “hybrid”. You can read and download a PDF Full Text of this paper here.