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Superparamagnetic Iron Oxide Nanoparticle Micelles Stabilized by Recombinant Oleosin for Targeted Magnetic Resonance Imaging

Kevin B. Vargo,Amr Zaki,Robert Warden-Rothman,Andrew Tsourkas,Daniel A. Hammer

Oleosin

Superparamagnetism

Recombinant DNA

2014

Recombinant surfactants present a new platform for stabilizing and targeting nanoparticle imaging agents. Superparamagnetic iron oxide nanoparticle-loaded micelles for MRI contrast are stabilized by an engineered variant of the naturally occurring protein oleosin and targeted using a Her2/neu affibody-oleosin fusion. The recombinant oleosin platform allows simple targeting and the ability to easily swap the ligand for numerous targets.

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“Superparamagnetic Iron Oxide Nanoparticle Micelles Stabilized by Recombinant Oleosin for Targeted Magnetic Resonance Imaging” is a paper by Kevin B. Vargo Amr Zaki Robert Warden-Rothman Andrew Tsourkas Daniel A. Hammer published in 2014. It has an Open Access status of “green”. You can read and download a PDF Full Text of this paper here.