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Here's everything you need to know about mental disorders from a research perspective

Top cited journal articles on the topic of mental disorders

Research on mental disorders has made significant progress in recent years, but there is still much that is not understood about the causes and best ways to treat these conditions. Some examples of areas of research on mental disorders include:

  • Understanding the genetic and environmental factors that contribute to the development of mental disorders such as depression, schizophrenia, and bipolar disorder
  • Examining the effectiveness of different treatment options, such as therapy, medication, and electroconvulsive therapy (ECT)
  • Investigating the neural mechanisms underlying mental disorders and how they may be targeted with new treatments
  • Improving diagnostic tools to more accurately identify and classify mental disorders
  • Identifying the best ways to deliver mental health services to different populations, such as veterans or individuals in rural communities
  • Examining the impact of lifestyle factors, such as diet and exercise, on mental health
  • Understanding the social determinants of mental health and how to address them

Overall, research on mental disorders aims to improve the understanding of these conditions, develop more effective treatments, and improve the quality of life for individuals living with mental illness.

It is important to note that research on mental disorders is ongoing, and new findings can lead to changes in diagnostic criteria, treatment recommendations, and our understanding of these conditions. And that it is important to work with a mental health professional to understand the best way to treat a mental disorder.

DOI: 10.1016/s2215-0366(21)00395-3
2022
Cited 313 times
Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
null
Years of potential life lost
Psychiatry
Eating disorders
DOI: 10.1016/j.jad.2021.09.098
2022
Cited 256 times
A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020
Eric Robinson, Angelina R. Sutin, Michael Daly, Andrew M. Jones
Mental health
Pandemic
Anxiety
DOI: 10.1038/s41591-022-01840-0
2022
Cited 128 times
Long COVID after breakthrough SARS-CoV-2 infection
Ziyad Al-Aly, Benjamin Bowe, Yan Xie
Medicine
Hazard ratio
Confidence interval
DOI: 10.1007/s11469-020-00356-3
2022
Cited 99 times
Validation of the Fear of COVID-19 Scale in a US College Sample
Catherine A. Perz, Brent A Lang, Rick Harrington
Anxiety
Clinical psychology
Psychology
DOI: 10.1038/s41386-021-01132-0
2022
Cited 94 times
The role of prefrontal cortex in cognitive control and executive function
Naomi P. Friedman, Trevor W. Robbins
Psychology
Prefrontal cortex
Working memory
DOI: 10.1136/bmj-2021-068993
2022
Cited 78 times
Risks of mental health outcomes in people with covid-19: cohort study
Yan Xie, Evan Xu, Ziyad Al-Aly
Hazard ratio
Medicine
Confidence interval
DOI: 10.1001/jama.2022.0040
2022
Cited 77 times
Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19
Hidde Heesakkers, Johannes H. van der Hoeven, Stijn Corsten, Inge Janssen, Esther Ewalds, Koen Simons, Brigitte Westerhof, Thijs C. D. Rettig, Crétien Jacobs, Susanne van Santen, Arjen J. C. Slooter, Margaretha C. E. van der Woude, Mark van den Boogaard, Marieke Zegers
Medicine
Intensive care unit
Hospital Anxiety and Depression Scale
DOI: 10.1016/j.euroneuro.2021.10.864
2022
Cited 63 times
The impact of the prolonged COVID-19 pandemic on stress resilience and mental health: A critical review across waves
Mirko Manchia, Anouk W. Gathier, Hale Yapici Eser, Mathias V. Schmidt, Dominique J.-F. de Quervain, Therese van Amelsvoort, Jonathan Ian Bisson, John F. Cryan, Oliver D. Howes, Luísa Pinto, Nic J.A. van der Wee, Katharina Domschke, Igor Branchi, Christiaan H. Vinkers
Pandemic
Mental health
Psychological resilience
DOI: 10.1016/j.jad.2021.11.031
2022
Cited 59 times
Long-term effects of COVID-19 on mental health: A systematic review
Nicole Wallbridge Bourmistrova, Tomas Solomon, Philip Braude, Rebecca Strawbridge, Ben Carter
Anxiety
Depression (economics)
Medicine
DOI: 10.4103/1673-5374.322423
2022
Cited 49 times
Microglia regulation of synaptic plasticity and learning and memory
Jessica Cornell, Shelbi Salinas, Hou Yuan Huang, Miou Zhou
Synaptic plasticity
Neuroscience
Microglia
DOI: 10.1016/s2215-0366(22)00260-7
2022
Cited 46 times
Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients
Maxime Taquet, Rebecca Sillett, Lena Zhu, Jacob Mendel, Isabella Camplisson, Quentin Dercon, Paul Harrison
Medicine
Cohort
Retrospective cohort study
DOI: 10.3390/antiox11020251
2022
Cited 45 times
The Role of Selenium in Pathologies: An Updated Review
Giulia Barchielli, Antonella Capperucci, Clemente Capasso
Selenocysteine
Selenium
Adverse Outcome Pathway
DOI: 10.15585/mmwr.su7102a1
2022
Cited 44 times
Mental Health Surveillance Among Children — United States, 2013–2019
Rebecca H. Bitsko, Angelika H. Claussen, Jesse Lichstein, Lindsey I. Black, Sherry Everett Jones, Melissa L. Danielson, Jennifer M. Hoenig, Shane P. Davis Jack, Debra J. Brody, Shiromani Gyawali, Matthew J. Maenner, Margaret Warner, Kristin M. Holland, Ruth Perou, Alex E. Crosby, Stephen J. Blumberg, Shelli Avenevoli, Jennifer W Kaminski, Reem M. Ghandour, Leah N. Meyer, null
Mental health
Psychological intervention
Psychiatry
DOI: 10.1038/s41380-022-01456-3
2022
Cited 41 times
A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia
Amelia J McGuinness, J. A. Davis, Samantha L. Dawson, Amy Loughman, F. Collier, M. O’Hely, C. A. Simpson, Jessica Green, Wolfgang Marx, C. Hair, G. Guest, M. Mohebbi, M. Berk, D. Stupart, D. Watters, Felice N. Jacka
Gut flora
Bipolar disorder
Schizophrenia (object-oriented programming)
DOI: 10.1111/jcpp.13445
2022
Cited 39 times
Prevalence of mental disorders in school children and adolescents in China: diagnostic data from detailed clinical assessments of 17,524 individuals
Fenghua Li, Yonghua Cui, Ying Li, Lanting Guo, Xiaoyan Ke, Jing Liu, Xuerong Luo, Yi Zheng, James F. Leckman
Epidemiology
Checklist
Stratified sampling
DOI: 10.1002/wps.20941
2022
Cited 38 times
The efficacy of psychotherapies and pharmacotherapies for mental disorders in adults: an umbrella review and meta‐analytic evaluation of recent meta‐analyses
Falk Leichsenring, Christiane Steinert, Sven Rabung, John P.A. Ioannidis
Medicine
Meta-analysis
Psychiatry
DOI: 10.1016/j.brainresbull.2022.02.004
2022
Cited 38 times
Brain–gut–microbiota axis in depression: A historical overview and future directions
Lijia Chang, Yan Wei, Kenji Hashimoto
Gut–brain axis
Gut flora
Depression (economics)
DOI: 10.1016/j.euroneuro.2021.10.004
2022
Cited 35 times
Results of the COVID-19 mental health international for the general population (COMET-G) study
Konstantinos N. Fountoulakis, Grigorios N Karakatsoulis, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D. Alarcón, Kiyomi Arai, Sani Salihu Auwal, Michael Berk, Sarah Bjedov, Julio Bobes, Teresa Bobes-Bascarán, Julie Bourgin-Duchesnay, C. Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby C. Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico De Berardis, Sergio Zamora Delgado, David Freitas de Lucena, Avinash De Sousa, Ramona Di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J. Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K. Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian Javier Garay, Leticia García-Álvarez, María Paz García-Portilla, Xenia Gonda, Tomasz M. Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, Tasdik M. Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jakobs, Miro Jakovljevic, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Ahmed Khalifa, Olena Khaustova, Steve Koh, Svetlana Kopishinskaia, Korneliia Kosenko, Sotirios A. Koupidis, Illés Kovács, Barbara Kulig, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López
Depression (economics)
Mental health
Anxiety
DOI: 10.1212/wnl.0000000000013225
2022
Cited 34 times
Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Patients With Parkinson Disease
Szu-Ju Chen, Ching-Chow Chen, Hsin-Yu Liao, Yating Lin, Yuwei Wu, Jyh-Ming Liou, Ming-Shiang Wu, Ching-Hua Kuo, Chin-Hsien Lin
Butyrate
Feces
Gut flora
DOI: 10.1136/bmj-2021-068414
2022
Cited 34 times
Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study
Ken Cohen, Sheng Ren, Kevin Heath, Micah C Dasmariñas, Karol Giuseppe Jubilo, Yinglong Guo, Marc Lipsitch, Sarah E Daugherty
Medicine
Confidence interval
Retrospective cohort study
DOI: 10.1038/s41390-021-01465-y
2022
Cited 33 times
Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood
Natasha Malik-Soni, Andrew Shaker, Helen Luck, Anne Mullin, Ryan E. Wiley, Mark P. Lewis, Joaquin Fuentes, Thomas W. Frazier
Health care
Autism spectrum disorder
Referral
DOI: 10.1002/wps.20943
2022
Cited 31 times
Validity and utility of Hierarchical Taxonomy of Psychopathology ( <scp>HiTOP</scp> ): <scp>III</scp> . Emotional dysfunction superspectrum
David I. Watson, Holly F. Levin-Aspenson, Monika A. Waszczuk, Christopher M. Conway, Tim Dalgleish, Michael N. Dretsch, Nicholas R. Eaton, Miriam K. Forbes, Kelsie T. Forbush, Kelsey A Hobbs, Giorgia Michelini, Brady D. Nelson, Martin Sellbom, Tim Slade, Susan C. South, Matthew Sunderland, Irwin D. Waldman, Michael Witthöft, Aidan G. C. Wright, Roman Kotov, Robert F. Krueger, Kamran Afzali, Marina A. Bornovalova, William T. Carpenter, Natacha Carragher, David C. Cicero, Danielle M. Dick, Anna R. Docherty, Michael B. First, Eiko I. Fried, Michael N. Hallquist, Katherine G. Jonas, Katherine M. Keyes, Robert D. Latzman, Kristian E. Markon, Les C. Morey, Stephanie N. Mullins‐Sweatt, Kristin Naragon‐Gainey, Thomas M. Olino, Praveetha Patalay, Christopher J. Patrick, Aaron L. Pincus, Ulrich Reininghaus, Craig Rodriguez-Seijas, Lauren A. Rutter, Giovanni Abrahão Salum, Alexander J. Shackman, Andrew E. Skodol, Tim Slade, Kathryn Tabb, Jennifer L. Tackett, Ashley L. Watts, Amanda A. Uliaszek, Thomas A. Widiger, David H. Zald, Johannes Zimmermann, Richard E. Zinbarg, null
Psychopathology
Neuroticism
Clinical psychology
DOI: 10.1001/jamanetworkopen.2022.0978
2022
Cited 31 times
Mental Health Outcomes in Transgender and Nonbinary Youths Receiving Gender-Affirming Care
Diana M Tordoff, Jonathon W Wanta, Arin Collin, Cesalie Stepney, David J Inwards-Breland, Kym Ahrens
Mental health
Medicine
Anxiety
DOI: 10.3390/biology11010061
2022
Cited 29 times
Psychological Symptoms in COVID-19 Patients: Insights into Pathophysiology and Risk Factors of Long COVID-19
Angel Yun-Kuan Thye, Jodi Woan-Fei Law, Loh Teng Hern Tan, Priyia Pusparajah, Hooi-Leng Ser, Sivakumar Thurairajasingam, Vengadesh Letchumanan, Learn Han Lee
Anxiety
Mental health
Depression (economics)
DOI: 10.1016/j.cmpb.2021.106541
2022
Cited 29 times
Application of artificial intelligence in wearable devices: Opportunities and challenges
Darius Nahavandi, Roohallah Alizadehsani, Abbas Khosravi, U. Rajendra Acharya
Wearable computer
Computer science
Wearable technology