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Biophysics (Page 1)

study of biological systems using methods from the physical sciences

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Papers in this category: 1 093 985 Current Page: 1 / 100

DOI: 10.1073/pnas.87.7.2466

Cited 2948 times

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

DOI: 10.1083/jcb.67.3.835

Cited 2941 times

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

DOI: 10.1038/312237a0

Cited 2924 times

Dynamic instability of microtubule growth

DOI: 10.1016/s0006-3495(00)76279-5

Cited 2919 times

Cell Movement Is Guided by the Rigidity of the Substrate

DOI: 10.1038/nprot.2006.202

Cited 2897 times

Using circular dichroism spectra to estimate protein secondary structure

DOI: 10.1126/science.285.5425.221

Cited 2892 times

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

DOI: 10.1073/pnas.93.24.13770

Cited 2891 times

Characterization of individual polynucleotide molecules using a membrane channel

DOI: 10.1016/0165-0270(91)90128-m

Cited 2878 times

A simple method for organotypic cultures of nervous tissue

DOI: 10.1126/science.276.5315.1109

Cited 2869 times

Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

DOI: 10.1124/pr.109.002451

Cited 2861 times

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

DOI: 10.1126/science.1077194

Cited 2855 times

In Vivo Imaging of Quantum Dots Encapsulated in Phospholipid Micelles

DOI: 10.1038/42264

Cited 2851 times

Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

DOI: 10.1038/370621a0

Cited 2850 times

Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria

DOI: 10.1046/j.1432-1327.2000.01606.x

Cited 2805 times

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

DOI: 10.1126/science.7684161

Cited 2798 times

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

DOI: 10.1038/228726a0

Cited 2788 times

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

DOI: 10.1073/pnas.88.11.4651

Cited 2788 times

Nitric oxide: an endogenous modulator of leukocyte adhesion.

DOI: 10.1111/j.1471-4159.1992.tb10990.x

Cited 2782 times

Reactive Oxygen Species and the Central Nervous System

DOI: 10.1093/nar/9.23.6505

Cited 2759 times

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

DOI: 10.1016/j.envexpbot.2007.05.011

Cited 2757 times

Heat tolerance in plants: An overview

DOI: 10.1073/pnas.94.25.13661

Cited 2753 times

Cell locomotion and focal adhesions are regulated by substrate flexibility

DOI: 10.1007/bf00289234

Cited 2696 times

A theory of biological pattern formation

DOI: 10.1038/309261a0

Cited 2681 times

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

DOI: 10.1016/j.addr.2006.09.020

Cited 2676 times

Thermo- and pH-responsive polymers in drug delivery☆

DOI: 10.1016/s0891-5849(00)00317-8

Cited 2658 times

Mitochondrial free radical generation, oxidative stress, and aging11This article is dedicated to the memory of our dear friend, colleague, and mentor Lars Ernster (1920–1998), in gratitude for all he gave to us.

DOI: 10.1038/205698a0

Cited 2650 times

Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

DOI: 10.1073/pnas.0608582104

Cited 2646 times

Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles

DOI: 10.1038/nature10361

Cited 2612 times

Crystal structure of the β2 adrenergic receptor–Gs protein complex

DOI: 10.1093/nar/16.13.6127

Cited 2603 times

High efficiency transformation of E.coli by high voltage electroporation

DOI: 10.1007/s40820-015-0040-x

Cited 2597 times

Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism

DOI: 10.1146/annurev.biochem.77.032207.120833

Cited 2596 times

Collagen Structure and Stability

DOI: 10.1016/0022-2836(70)90051-3

Cited 2591 times

Calcium-dependent bacteriophage DNA infection

DOI: 10.1126/science.1281928

Cited 2577 times

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

DOI: 10.1073/pnas.0805135105

Cited 2568 times

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

DOI: 10.1073/pnas.72.5.1858

Cited 2563 times

A protein factor essential for microtubule assembly.

DOI: 10.1038/374517a0

Cited 2552 times

Crystal structure of an integral membrane light-harvesting complex from photosynthetic bacteria

DOI: 10.1073/pnas.0801763105

Cited 2544 times

The effect of particle design on cellular internalization pathways

DOI: 10.1126/science.1124618

Cited 2540 times

The Fluorescent Toolbox for Assessing Protein Location and Function

DOI: 10.1038/ni.1631

Cited 2527 times

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

DOI: 10.1038/306067a0

Cited 2523 times

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

DOI: 10.1126/science.aaf4382

Cited 2522 times

Liquid phase condensation in cell physiology and disease

DOI: 10.1038/nbt0102-87

Cited 2511 times

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

DOI: 10.1038/366575a0

Cited 2497 times

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid

DOI: 10.1038/nsb0902-646

Cited 2487 times

Molecular dynamics simulations of biomolecules

DOI: 10.1073/pnas.37.4.205

Cited 2482 times

The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain

DOI: 10.1042/bj20031253

Cited 2475 times

Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

DOI: 10.1126/science.271.5250.795

Cited 2468 times

Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules

DOI: 10.1046/j.1365-2958.1998.01062.x

Cited 2455 times

Flagellar and twitching motility are necessary for <i>Pseudomonas aeruginosa</i> biofilm development

DOI: 10.1126/science.256.5060.1217

Cited 2431 times

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

DOI: 10.1016/0143-4160(86)90026-6

Cited 2429 times

A model for receptor-regulated calcium entry

DOI: 10.1146/annurev.biochem.69.1.531

Cited 2422 times

Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin

DOI: 10.1038/35014014

Cited 2421 times

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

DOI: 10.1016/s0092-8674(00)81717-1

Cited 2421 times

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

DOI: 10.1093/jexbot/53.366.1

Cited 2417 times

Cellular mechanisms for heavy metal detoxification and tolerance

DOI: 10.1038/nnano.2008.30

Cited 2414 times

Nanoparticle-mediated cellular response is size-dependent

DOI: 10.1385/mb:26:3:249

Cited 2405 times

The Comet Assay for DNA Damage and Repair: Principles, Applications, and Limitations

DOI: 10.1152/physrev.1981.61.2.296

Cited 2401 times

Intracellular pH.

DOI: 10.1038/289366a0

Cited 2397 times

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

DOI: 10.1038/nature02196

Cited 2397 times

TRP channels as cellular sensors

DOI: 10.1016/s0092-8674(03)00801-8

Cited 2392 times

Functional siRNAs and miRNAs Exhibit Strand Bias

DOI: 10.1083/jcb.34.1.207

Cited 2389 times

FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

DOI: 10.1073/pnas.91.22.10625

Cited 2379 times

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

DOI: 10.1101/cshperspect.a000414

Cited 2378 times

The Bacterial Cell Envelope

DOI: 10.1126/science.6243188

Cited 2356 times

Calmodulin Plays a Pivotal Role in Cellular Regulation

DOI: 10.1038/273345a0

Cited 2352 times

Role of cell shape in growth control

DOI: 10.1007/s00018-004-4464-6

Cited 2352 times

Hsp70 chaperones: Cellular functions and molecular mechanism

DOI: 10.1016/j.addr.2008.03.016

Cited 2347 times

Gold nanoparticles in delivery applications☆

DOI: 10.1006/nimg.2002.1267

Cited 2344 times

Dysmyelination Revealed through MRI as Increased Radial (but Unchanged Axial) Diffusion of Water

DOI: 10.1016/0005-2728(96)00022-9

Cited 2334 times

The ferritins: molecular properties, iron storage function and cellular regulation

DOI: 10.1016/j.cbpa.2003.08.007

Cited 2333 times

In vivo near-infrared fluorescence imaging

DOI: 10.1038/nbt764

Cited 2323 times

Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

DOI: 10.1186/1556-276x-8-102

Cited 2314 times

Liposome: classification, preparation, and applications

DOI: 10.1002/j.1460-2075.1985.tb03825.x

Cited 2311 times

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

DOI: 10.1038/28190

Cited 2311 times

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

DOI: 10.1016/s0142-9612(03)00343-0

Cited 2306 times

RGD modified polymers: biomaterials for stimulated cell adhesion and beyond

DOI: 10.1038/416507a

Cited 2303 times

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

DOI: 10.1073/pnas.1936192100

Cited 2301 times

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

DOI: 10.1016/0092-8674(95)90340-2

Cited 2299 times

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

DOI: 10.1083/jcb.40.3.648

Cited 2298 times

JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN

DOI: 10.1038/320454a0

Cited 2298 times

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

DOI: 10.1126/science.1853201

Cited 2282 times

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

DOI: 10.1016/0022-2836(67)90353-1

Cited 2269 times

A fluorescent complex between ethidium bromide and nucleic acids

DOI: 10.1038/35082000

Cited 2269 times

Three-dimensional structure of cyanobacterial photosystem I at 2.5 Å resolution

DOI: 10.1038/nnano.2007.70

Cited 2263 times

Shape effects of filaments versus spherical particles in flow and drug delivery

DOI: 10.1146/annurev.bi.47.070178.004131

Cited 2258 times

Fluorescence Energy Transfer as a Spectroscopic Ruler

DOI: 10.1038/305147a0

Cited 2257 times

ATP-regulated K+ channels in cardiac muscle

DOI: 10.1146/annurev.cellbio.13.1.83

Cited 2246 times

MICROTUBULE POLYMERIZATION DYNAMICS

DOI: 10.1002/j.1460-2075.1982.tb01257.x

Cited 2238 times

Gene transfer into mouse lyoma cells by electroporation in high electric fields.

DOI: 10.1038/nature719

Cited 2231 times

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

DOI: 10.1038/260799a0

Cited 2224 times

Single-channel currents recorded from membrane of denervated frog muscle fibres

DOI: 10.1038/26412

Cited 2223 times

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

DOI: 10.1002/smll.200901158

Cited 2222 times

Effect of Surface Properties on Nanoparticle–Cell Interactions

DOI: 10.1016/0304-4157(95)00003-a

Cited 2220 times

The mitochondrial permeability transition

DOI: 10.1073/pnas.082243699

Cited 2218 times

A monomeric red fluorescent protein

DOI: 10.1083/jcb.94.2.325

Cited 2213 times

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

DOI: 10.1016/s0092-8674(00)80760-6

Cited 2208 times

Mammalian Telomeres End in a Large Duplex Loop

DOI: 10.1073/pnas.95.8.4607

Cited 2206 times

Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

DOI: 10.1038/25764

Cited 2203 times

Three-dimensional segregation of supramolecular activation clusters in T cells

DOI: 10.1038/372055a0

Cited 2195 times

Mechanisms of intracellular protein transport

DOI: 10.1038/35067088

Cited 2192 times

Multifunctional strands in tight junctions

Papers in this category: 1 093 985 Current Page: 1 / 100