S. Banerjee

The L3 experiment is one of the six large detectors designed for the new generation of electron-positron accelerators. It is the only detector that concentrates its efforts on limited goals of measuring electrons, muons and photons. By not attempting to identify hadrons, L3 has been able to provide an order of magnitude better resolution for electrons, muons and photons. Vertices and hadron jets are also studied. The construction of L3 has involved much state of the art technology in new principles of vertex detection and in new crystals for large scale electromagnetic shower detection and ultraprecise muon detection. This paper presents a summary of the construction of L3.

We report the observation of the X(3872) in the J/psipi(+)pi(-) channel, with J/psi decaying to mu(+)mu(-), in pp collisions at sqrt[s]=1.96 TeV. Using approximately 230 pb(-1) of data collected with the Run II D0 detector, we observe 522+/-100 X(3872) candidates. The mass difference between the X(3872) state and the J/psi is measured to be 774.9+/-3.1(stat)+/-3.0(syst) MeV/c(2). We have investigated the production and decay characteristics of the X(3872) and find them to be similar to those of the psi(2S) state.

This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C. Please note that version 3 on the archive is the auxiliary version of the Physics of the B Factories book. This uses the notation alpha, beta, gamma for the angles of the Unitarity Triangle. The nominal version uses the notation phi_1, phi_2 and phi_3. Please cite this work as Eur. Phys. J. C74 (2014) 3026.

Matrix metalloproteinases (MMPs) are zinc dependent proteolytic metalloenzyme. MMP-9 is one of the most complex forms of matrix metalloproteinases. MMP-9 has the ability to degrade the extracellular matrix (ECM) components and has important role in the pathophysiological functions. Overexpression and dysregulation of MMP-9 is associated with various diseases. Thus, regulation and inhibition of MMP-9 is an important therapeutic approach for combating various diseases including cancer. Inhibitors of MMP-9 can be used as anticancer agents. Till date no selective MMP-9 inhibitors passed the clinical trials. In this review the structure, activation, function and inhibitors of MMP-9 are mainly focused. Some highly active and/or selective MMP-9 inhibitors have been discussed which may be helpful to explore the structural significance of MMP-9 inhibitors. This study may be useful to design new potent and selective MMP-9 inhibitors against cancer in future.

We report observation of the electroweak production of single top quarks in pp[over ] collisions at sqrt[s]=1.96 TeV based on 2.3 fb(-1) of data collected by the D0 detector at the Fermilab Tevatron Collider. Using events containing an isolated electron or muon and missing transverse energy, together with jets originating from the fragmentation of b quarks, we measure a cross section of sigma(pp[over ]--> tb + X, tqb + X) = 3.94 + or - 0.88 pb. The probability to measure a cross section at this value or higher in the absence of signal is 2.5 x 10(-7), corresponding to a 5.0 standard deviation significance for the observation.

We search for single-photon events in 53 fb^{-1} of e^{+}e^{-} collision data collected with the BABAR detector at the PEP-II B-Factory. We look for events with a single high-energy photon and a large missing momentum and energy, consistent with production of a spin-1 particle A^{'} through the process e^{+}e^{-}→γA^{'}; A^{'}→invisible. Such particles, referred to as "dark photons," are motivated by theories applying a U(1) gauge symmetry to dark matter. We find no evidence for such processes and set 90% confidence level upper limits on the coupling strength of A^{'} to e^{+}e^{-} in the mass range m_{A^{'}}≤8 GeV. In particular, our limits exclude the values of the A^{'} coupling suggested by the dark-photon interpretation of the muon (g-2)_{μ} anomaly, as well as a broad range of parameters for the dark-sector models.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of COVID-19 caused by SARS-CoV-2. In this scenario, viral protease enzymes are crucial targets for drug discovery. This extensive study meticulously focused on two viral proteases such as main protease (Mpro) and papain-like protease (PLpro), those are essential for viral replication. This review provides a detail overview of the targets (Mpro and PLpro) from a structural and medicinal chemistry point of view, together with recently reported protease inhibitors. An insight into the challenges in the development of effective as well as drug like protease inhibitors is discussed. Peptidomimetic and/or covalent coronavirus protease inhibitors possessed potent and selective active site inhibition but compromised in pharmacokinetic parameters to be a drug/drug like molecule. Lead optimization of non-peptidomimetic and/or low molecular weight compounds may be a better option for oral delivery. A masterly combination of adequate pharmacokinetic properties with coronavirus protease activity as well as selectivity will provide potential drug candidates in future. This study is a part of our endeavors which surely dictates medicinal chemistry efforts to discover effective anti-viral agent for this devastating disease.

We study the Dalitz plot of the decay D(+)-->K(-)pi(+)pi(+) with a sample of 15090 events from Fermilab experiment E791. Modeling the decay amplitude as the coherent sum of known Kpi resonances and a uniform nonresonant term, we do not obtain an acceptable fit. If we allow the mass and width of the K(*)(0)(1430) to float, we obtain values consistent with those from PDG but the chi(2) per degree of freedom of the fit is still unsatisfactory. A good fit is found when we allow for the presence of an additional scalar resonance, with mass 797+/-19+/-43 MeV/c(2) and width 410+/-43+/-87 MeV/c(2). The mass and width of the K(*)(0)(1430) become 1459+/-7+/-5 MeV/c(2) and 175+/-12+/-12 MeV/c(2), respectively. Our results provide new information on the scalar sector in hadron spectroscopy.

We report the results of first physics runs of the L3 detector at LEP. Based on 2538 hadron events, we determined the mass mz0 and the width Γz0 of the intermediate vector boson Z0 to be mz0=91.132±0.057 GeV (not including the 46 MeV LEP machine energy uncertainty) and Γz0=2.588±0.137 GeV. We also determined Γinvisible=0.567±0.080 GeV, corresponding to 3.42±0.48 number of neutrino flavors. We also measured the muon pair cross section and determined the branching ratio Γμμ=Γh=0.056±0.006. The partial width of Z0→e+e− is Γee=88±9±7 MeV.

We report results of a study of the B(s)(0) oscillation frequency using a large sample of B(s)(0) semileptonic decays corresponding to approximately 1 fb(-1) of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron Collider in 2002-2006. The amplitude method gives a lower limit on the B(s)(0) oscillation frequency at 14.8 ps(-1) at the 95% C.L. At delta m(s) = 19 ps(-1), the amplitude deviates from the hypothesis A= 0(1) by 2.5 (1.6) standard deviations, corresponding to a two-sided C.L. of 1% (10%). A likelihood scan over the oscillation frequency, delta m(s), gives a most probable value of 19 ps(-1) and a range of 17 < delta m(s) < 21 ps(-1)at the 90% C.L., assuming Gaussian uncertainties. This is the first direct two-sided bound measured by a single experiment. If delta m(s) lies above 22 ps(-1), then the probability that it would produce a likelihood minimum similar to the one observed in the interval 16-22 ps(-1) is (5.0 +/- 0.3)%.

We measure the charge asymmetry A ≡ (N++ - N--)/(N++ + N--) of like-sign dimuon events in 6.1 fb-1 of pp collisions recorded with the D0 detector at a center-of-mass energy square root(s) = 1.96 TeV at the Fermilab Tevatron collider. From A we extract the like-sign dimuon charge asymmetry in semileptonic b-hadron decays: A(sl)(b) = -0.009 57 ± 0.002 51(stat) ± 0.001 46(sys). It differs by 3.2 standard deviations from the standard model prediction A(sl)(b)(SM) = (-2.3(-0.6)(+0.5)) × 10(-4), and provides first evidence of anomalous CP violation in the mixing of neutral B mesons.

X-ray screening systems have been used to safeguard environments in which access control is of paramount importance. Security checkpoints have been placed at the entrances to many public places to detect prohibited items, such as handguns and explosives. Generally, human operators are in charge of these tasks as automated recognition in baggage inspection is still far from perfect. Research and development on X-ray testing is, however, exploring new approaches based on computer vision that can be used to aid human operators. This paper attempts to make a contribution to the field of object recognition in X-ray testing by evaluating different computer vision strategies that have been proposed in the last years. We tested ten approaches. They are based on bag of words, sparse representations, deep learning, and classic pattern recognition schemes among others. For each method, we: 1) present a brief explanation; 2) show experimental results on the same database; and 3) provide concluding remarks discussing pros and cons of each method. In order to make fair comparisons, we define a common experimental protocol based on training, validation, and testing data (selected from the public GDXray database). The effectiveness of each method was tested in the recognition of three different threat objects: 1) handguns; 2) shuriken (ninja stars); and 3) razor blades. In our experiments, the highest recognition rate was achieved by methods based on visual vocabularies and deep features with more than 95% of accuracy. We strongly believe that it is possible to design an automated aid for the human inspection task using these computer vision algorithms.

We measure the charge asymmetry $A$ of like-sign dimuon events in 6.1 fb$^{-1}$ of $p\bar{p}$ collisions recorded with the D0 detector at a center-of-mass energy $\sqrt{s} = 1.96$ TeV at the Fermilab Tevatron collider. From $A$, we extract the like-sign dimuon charge asymmetry in semileptonic $b$-hadron decays: $\aslb = -0.00957 \pm 0.00251 ({\rm stat}) \pm 0.00146 ({\rm syst})$. This result differs by 3.2 standard deviations from the standard model prediction $\aslb(SM) = (-2.3^{+0.5}_{-0.6}) \times 10^{-4}$ and provides first evidence of anomalous CP-violation in the mixing of neutral $B$ mesons.

We present a measurement of the W boson mass using data corresponding to 4.3fb^-1 of integrated luminosity collected with the D0 detector during Run II at the Fermilab Tevatron p\bar{p} collider. With a sample of 1,677,394 W -> e\nu candidate events, we measure M_W = 80.367 +/- 0.026 GeV. This result is combined with an earlier D0 result determined using an independent Run II data sample, corresponding to 1fb^-1 of integrated luminosity, to yield M_W = 80.375 +/- 0.023 GeV.

Among different Histone deacetylases (HDACs), histone deacetylase 3 (HDAC3) is an epigenetic drug target which is currently marked as a potential therapeutic strategy to combat various cancers. HDAC3 inhibitors are effective for the treatment of cancers, different neurodegenerative disorders, diabetes mellitus, cardiac diseases, HIV, inflammatory diseases, rheumatoid arthritis (RA), etc. Inhibition of HDAC3 metalloenzyme is a dynamic approach for drug design and discovery. This approach has gained considerable interest in recent years. The development of an effective therapeutic agent against HDAC3 is still challenging. A lot of work is still in demand. This current communication is a part of our extended work on HDAC3 inhibitors to achieve deep insight of knowledge about the structural information of HDAC3 inhibitors. This article is unique in terms of detailed structure-activity relationships (SARs) analysis. This may help to find out some important clues to design better active HDAC3 inhibitors in the future.

The histone deacetylases (HDACs) enzymes provided crucial role in transcriptional regulation of cells through deacetylation of nuclear histone proteins. Discoveries related to the HDAC8 enzyme activity signified the importance of HDAC8 isoform in cell proliferation, tumorigenesis, cancer, neuronal disorders, parasitic/viral infections and other epigenetic regulations. The pan-HDAC inhibitors can confront these conditions but have chances to affect epigenetic functions of other HDAC isoforms. Designing of selective HDAC8 inhibitors is a key feature to combat the pathophysiological and diseased conditions involving the HDAC8 activity. This review is concerned about the structural and positional aspects of HDAC8 in the HDAC family. It also covers the contributions of HDAC8 in the pathophysiological conditions, a preliminary discussion about the recent scenario of HDAC8 inhibitors. This review might help to deliver the structural, functional and computational information in order to identify and design potent and selective HDAC8 inhibitors for target specific treatment of diseases involving HDAC8 enzymatic activity.

COVID-19 is the most devastating disease in recent times affecting most people globally. The higher rate of transmissibility and mutations of SARS-CoV-2 along with the lack of potential therapeutics has made it a global crisis. Potential molecules from natural sources could be a fruitful remedy to combat COVID-19. This systematic review highlights the detailed therapeutic implication of naturally occurring glycyrrhizin and its related derivatives against COVID-19. Glycyrrhizin has already been established for blocking different biomolecular targets related to the SARS-CoV-2 replication cycle. In this article, several experimental and theoretical evidences of glycyrrhizin and related derivatives have been discussed in detail to evaluate their potential as a promising therapeutic strategy against COVID-19. Moreover, the implication of glycyrrhizin in traditional Chinese medicines for alleviating the symptoms of COVID-19 has been reviewed. The potential role of glycyrrhizin and related compounds in affecting various stages of the SARS-CoV-2 life cycle has also been discussed in detail. Derivatization of glycyrrhizin for designing potential lead compounds along with combination therapy with other anti-SARS-CoV-2 agents followed by extensive evaluation may assist in the formulation of novel anti-coronaviral therapy for better treatment to combat COVID-19.

Identification of key structural features of meprin β inhibitors by ML models and binding mode of interaction analysis.

Histone deacetylase 3 (HDAC3) is an epigenetic regulator that involves gene expression, apoptosis, and cell cycle progression, and the overexpression of HDAC3 is accountable for several cancers, neurodegeneracy, and many other diseases. Therefore, HDAC3 emerged as a promising drug target for the novel drug design. Here, we carried out the pharmacophore modeling using 50 benzamide-based HDAC3 selective inhibitors and utilized it for PHASE ligand screening to retrieve the hits with similar pharmacophore features. The dataset inhibitors of best hypotheses used to build the 3D QSAR model and the generated 3D QSAR model resulted in good PLS statistics with a regression coefficient (R2) of 0.89, predictive coefficient (Q2) of 0.88, and Pearson-R factor of 0.94 indicating its excellent predictive ability. The hits retrieved from pharmacophore-based virtual screening were subjected to docking against HDAC3 for the identification of potential inhibitors. A total of 10 hitsM1 to M10 were ranked using their scoring functions and further subject to lead optimization. The Prime MM/GBSA, AutoDock binding free energies, and ADMET studies were implemented for the selection of lead candidates. The four ligand molecules M1, M2, M3, and M4 were identified as potential leads against HDAC3 after lead optimization. The top two leads M1 and M2 were subjected to MD simulations for their stability evaluation with HDAC3. The newly designed leads M11 and M12 were identified as HDAC3 potential inhibitors from MD simulations studies. Therefore, the outcomes of the present study could provide insights into the discovery of new potential HDAC3 inhibitors with improved selectivity and activity against a variety of cancers and neurodegenerative diseases.

We report evidence for the decay ${B}^{0}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{0}{\ensuremath{\pi}}^{0}$. The analysis is based on a data sample of ${\mathrm{152}\mathrm{\ifmmode\times\else\texttimes\fi{}}\mathrm{10}}^{6}$ $B\overline{B}$ pairs collected at the $\ensuremath{\Upsilon}(4S)$ resonance with the Belle detector at the KEKB ${e}^{+}{e}^{\ensuremath{-}}$ storage ring. We detect a signal for ${B}^{0}\ensuremath{\rightarrow}{\ensuremath{\pi}}^{0}{\ensuremath{\pi}}^{0}$ with a significance of 3.4 standard deviations, and measure the branching fraction to be $\mathrm{[}\mathrm{1.7}\ifmmode\pm\else\textpm\fi{}\mathrm{0.6}\mathrm{(}\mathrm{s}\mathrm{t}\mathrm{a}\mathrm{t}\mathrm{)}\ifmmode\pm\else\textpm\fi{}\mathrm{0.2}\mathrm{(}\mathrm{s}\mathrm{y}\mathrm{s}\mathrm{t}\mathrm{)}\mathrm{]}\ifmmode\times\else\texttimes\fi{}{\mathrm{10}}^{\ensuremath{-}\mathrm{6}}$.

A search for exotic unstable neutral and charged heavy leptons as well as for stable charged heavy leptons is performed with the L3 detector at LEP. Sequential, vector and mirror natures of heavy leptons are considered. No evidence for their existence is found and lower limits on their masses are set.

We describe the design, construction and performance of the upgraded DO muon system for Run II of the Fermilab Tevatron collider. Significant improvements have been made to the major subsystems of the DO muon detector: trigger scintillation counters, tracking detectors, and electronics. The Run II central muon detector has a new scintillation counter system inside the iron toroid and an improved scintillation counter system outside the iron toroid. In the forward region, new scintillation counter and tracking systems have been installed. Extensive shielding has been added in the forward region. A large fraction of the muon system electronics is also new.

The D0 collaboration has performed a measurement of the top quark mass based on six candidate events for the process t tbar -&gt; b W+ bbar W-, where the W bosons decay to e nu or mu nu. This sample was collected during an exposure of the D0 detector to an integrated luminosity of 125 pb^-1 of sqrt(s)=1.8 TeV p-pbar collisions. We obtain mt = 168.4 +- 12.3 (stat) +- 3.7 (sys) GeV/c^2, consistent with the measurement obtained using single-lepton events. Combination of the single-lepton and dilepton results yields mt = 172.0 +- 7.5 GeV/c^2.

We determine the top quark mass mt using tt¯ pairs produced in the DØ detector by s=1.8TeV pp¯ collisions in a 125pb−1 exposure at the Fermilab Tevatron. We make a two constraint fit to mt in tt¯→bW+b¯W− final states with one W boson decaying to qq¯ and the other to eν or μν. Likelihood fits to the data yield mt(l+jets)=173.3±5.6(stat)±5.5(syst) GeV/c2. When this result is combined with an analysis of events in which both W bosons decay into leptons, we obtain mt=172.1±5.2(stat)±4.9(syst) GeV/c2. An alternate analysis, using three constraint fits to fixed top quark masses, gives mt(l+jets)=176.0±7.9(stat)±4.8(syst) GeV/c2, consistent with the above result. Studies of kinematic distributions of the top quark candidates are also presented. 14.65.Ha, 13.85.Ni, 13.85.QkReceived 27 January 1998DOI:https://doi.org/10.1103/PhysRevD.58.052001©1998 American Physical Society

Single- and multi-photon events with missing energy are selected in 619 pb−1 of data collected by the L3 detector at LEP at centre-of-mass energies between 189 and 209 GeV. The cross sections of the process e+e−→νν̄γ(γ) are found to be in agreement with the Standard Model expectations, and the number of light neutrino species is determined, including lower energy data, to be Nν=2.98±0.05±0.04. Selection results are given in the form of tables which can be used to test future models involving single- and multi-photon signatures at LEP. These final states are also predicted by models with large extra dimensions and by several supersymmetric models. No evidence for such models is found. Among others, lower limits between 1.5 and 0.65 TeV are set, at 95% confidence level, on the new scale of gravity for the number of extra dimensions between 2 and 6.

We report the observation of an isotriplet of excited charmed baryons, decaying into Lambda(+)(c)pi(-), Lambda(+)(c)pi(0), and Lambda(+)(c)pi(+). We measure the mass differences M(Lambda(+)(c)pi)-M(Lambda(+)(c)) and widths to be 515.4(+3.2+2.1)(-3.1-6.0) MeV/c(2), 61(+18+22)(-13-13) MeV for the neutral state; 505.4(+5.8+12.4)(-4.6-2.0) MeV/c(2), 62(+37+52)(-23-38) MeV for the charged state; and 514.5(+3.4+2.8)(-3.1-4.9) MeV/c(2), 75(+18+12)(-13-11) MeV for the doubly charged state, where the uncertainties are statistical and systematic, respectively. These results are obtained from a 281 fb(-1) data sample collected with the Belle detector near the Upsilon(4S) resonance, at the KEKB asymmetric energy e(+)e(-) collider.

A data sample corresponding to an integrated luminosity of 2.1 fb−1 collected by the DØ detector at the Fermilab Tevatron Collider was analyzed to search for squarks and gluinos produced in pp¯ collisions at a center-of-mass energy of 1.96 TeV. No evidence for the production of such particles was observed in topologies involving jets and missing transverse energy, and 95% C.L. lower limits of 379 GeV and 308 GeV were set on the squark and gluino masses, respectively, within the framework of minimal supergravity with tanβ=3, A0=0, and μ<0. The corresponding previous limits are improved by 54 GeV and 67 GeV.

The D0 Collaboration presents first evidence for the production of single top quarks at the Fermilab Tevatron pp[over ] collider. Using a 0.9 fb(-1) dataset, we apply a multivariate analysis to separate signal from background and measure sigma(pp[over ]-->tb+X,tqb+X)=4.9+/-1.4 pb. The probability to measure a cross section at this value or higher in the absence of a signal is 0.035%, corresponding to a 3.4 standard deviation significance. We use the cross section measurement to directly determine the Cabibbo-Kobayashi-Maskawa matrix element that describes the Wtb coupling and find 0.68<|V(tb)|</=1 at 95% C.L. within the standard model.

We present a measurement of the shape of the $Z/{\ensuremath{\gamma}}^{*}$ boson transverse momentum (${q}_{T}$) distribution in $p\overline{p}\ensuremath{\rightarrow}Z/{\ensuremath{\gamma}}^{*}\ensuremath{\rightarrow}{e}^{+}{e}^{\ensuremath{-}}+X$ events at a center-of-mass energy of 1.96 TeV using $0.98\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data collected with the D0 detector at the Fermilab Tevatron collider. The data are found to be consistent with the resummation prediction at low ${q}_{T}$, but above the perturbative QCD calculation in the region of ${q}_{T}&gt;30\text{ }\text{ }\mathrm{GeV}/c$. Using events with ${q}_{T}&lt;30\text{ }\text{ }\mathrm{GeV}/c$, we extract the value of ${g}_{2}$, one of the nonperturbative parameters for the resummation calculation. Data at large boson rapidity $y$ are compared with the prediction of resummation and with alternative models that employ a resummed form factor with modifications in the small Bjorken $x$ region of the proton wave function.

We report the first direct observation of the strange b baryon Xi(b)- (Xi(b)+). We reconstruct the decay Xi(b)- -->J/psiXi-, with J/psi-->mu+mu-, and Xi--->Lambdapi--->ppi-pi- in pp collisions at square root of s =1.96 TeV. Using 1.3 fb(-1) of data collected by the D0 detector, we observe 15.2 +/- 4.4(stat)(-0.4)(+1.9)(syst) Xi(b)- candidates at a mass of 5.774 +/- 0.011(stat) +/- 0.015(syst) GeV. The significance of the observed signal is 5.5 sigma, equivalent to a probability of 3.3 x 10(-8) of it arising from a background fluctuation. Normalizing to the decay Lambda(b)-->J/psiLambda, we measure the relative rate sigma(Xi(b-) x B(Xi)b})- -->J/psiXi-)/sigma(Lambda(b)) x B(Lambda(b)-->J/psiLambda) = 0.28+/-0.09(stat)(-0.08)(+0.09)(syst).

We measure the charge asymmetry $A\equiv(N^{++} - N^{--})/(N^{++} + N^{--})$ of like-sign dimuon events in 6.1~fb$^{-1}$ of $p\bar{p}$ collisions recorded with the D0 detector at a center-of-mass energy $\sqrt{s}=1.96$~TeV at the Fermilab Tevatron collider. From $A$ we extract the like-sign dimuon charge asymmetry in semileptonic $b$-hadron decays: $\aslb=-0.00957\pm0.00251\thinspace({\rm stat})\pm0.00146\thinspace({\rm sys})$. It differs by 3.2~standard deviations from the standard model prediction $\aslb({\rm SM})=(-2.3^{+0.5}_{-0.6})\times10^{-4}$, and provides first evidence of anomalous $CP$ violation in the mixing of neutral $B$ mesons.

We present first evidence for the production of single top quarks in the D0 detector at the Fermilab Tevatron ppbar collider. The standard model predicts that the electroweak interaction can produce a top quark together with an antibottom quark or light quark, without the antiparticle top quark partner that is always produced from strong coupling processes. Top quarks were first observed in pair production in 1995, and since then, single top quark production has been searched for in ever larger datasets. In this analysis, we select events from a 0.9 fb-1 dataset that have an electron or muon and missing transverse energy from the decay of a W boson from the top quark decay, and two, three, or four jets, with one or two of the jets identified as originating from a b hadron decay. The selected events are mostly backgrounds such as W+jets and ttbar events, which we separate from the expected signals using three multivariate analysis techniques: boosted decision trees, Bayesian neural networks, and matrix element calculations. A binned likelihood fit of the signal cross section plus background to the data from the combination of the results from the three analysis methods gives a cross section for single top quark production of 4.7 +- 1.3 pb. The probability to measure a cross section at this value or higher in the absence of signal is 0.014%, corresponding to a 3.6 standard deviation significance. The measured cross section value is compatible at the 10% level with the standard model prediction for electroweak top quark production.

This article reports world averages for measurements of b-hadron, c-hadron, and tau-lepton properties obtained by the Heavy Flavor Averaging Group (HFAG) using results available at least through the end of 2009. Some of the world averages presented use data available through the spring of 2010. For the averaging, common input parameters used in the various analyses are adjusted (rescaled) to common values, and known correlations are taken into account. The averages include branching fractions, lifetimes, neutral meson mixing parameters, CP violation parameters, and parameters of semileptonic decays.

We present the first measurement of dijet angular distributions in ppbar collisions at sqrt{s}=1.96TeV at the Fermilab Tevatron Collider. The measurement is based on a dataset corresponding to an integrated luminosity of up to 0.7fb-1 collected with the D0 detector. Dijet angular distributions have been measured over a range of dijet masses, from 0.25TeV to above 1.1TeV. The data are in good agreement with the predictions of perturbative QCD and are used to constrain new physics models including quark compositeness, large extra dimensions, and TeV-1 scale extra dimensions. For all models we set the most stringent direct limits to date.

We present an improved determination of the total width of the top quark, $Γ_t$, using 5.4 fb$^{-1}$ of integrated luminosity collected by the D0 Collaboration at the Tevatron $p\bar{p}$ Collider. The total width $Γ_t$ is extracted from the partial decay width $Γ(t\to Wb)$ and the branching fraction $\mathcal{B}(t\to Wb)$. $Γ(t\to Wb)$ is obtained from the $t$-channel single top quark production cross section and $\mathcal{B}(t\to Wb)$ is measured in $t\bar{t}$ events. For a top mass of $172.5\;\rm GeV$, the resulting width is $Γ_t = 2.00^{+0.47}_{-0.43}$ GeV. This translates to a top-quark lifetime of $τ_t = (3.29^{+0.90}_{-0.63})\times10^{-25}$ s. We also extract an improved direct limit on the CKM matrix element $0.81 &lt; |V_{tb}| \leq 1$ at 95% C.L. and a limit of $|V_{tb'}| &lt; 0.59$ for a high mass fourth generation bottom quark assuming unitarity of the fourth generation quark mixing matrix.

We present the final combination of CDF and D0 measurements of cross sections for single-top-quark production in proton-antiproton collisions at a center-of-mass energy of 1.96 TeV. The data correspond to total integrated luminosities of up to 9.7 fb^{-1} per experiment. The t-channel cross section is measured to be σ_{t}=2.25_{-0.31}^{+0.29} pb. We also present the combinations of the two-dimensional measurements of the s- vs t-channel cross section. In addition, we give the combination of the s+t channel cross section measurement resulting in σ_{s+t}=3.30_{-0.40}^{+0.52} pb, without assuming the standard model value for the ratio σ_{s}/σ_{t}. The resulting value of the magnitude of the top-to-bottom quark coupling is |V_{tb}|=1.02_{-0.05}^{+0.06}, corresponding to |V_{tb}|>0.92 at the 95% C.L.

We present a search for the direct production of a light pseudoscalar a decaying into two photons with the Belle II detector at the SuperKEKB collider. We search for the process e^{+}e^{-}→γa, a→γγ in the mass range 0.2<m_{a}<9.7 GeV/c^{2} using data corresponding to an integrated luminosity of (445±3) pb^{-1}. Light pseudoscalars interacting predominantly with standard model gauge bosons (so-called axionlike particles or ALPs) are frequently postulated in extensions of the standard model. We find no evidence for ALPs and set 95% confidence level upper limits on the coupling strength g_{aγγ} of ALPs to photons at the level of 10^{-3} GeV^{-1}. The limits are the most restrictive to date for 0.2<m_{a}<1 GeV/c^{2}.

Main protease (Mpro) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) intervenes in the replication and transcription processes of the virus. Hence, it is a lucrative target for anti-viral drug development. In this study, molecular modeling analyses were performed on the structure activity data of recently reported diverse SARS-CoV-2 Mpro inhibitors to understand the structural requirements for higher inhibitory activity. The classification-based quantitative structure-activity relationship (QSAR) models were generated between SARS-CoV-2 Mpro inhibitory activities and different descriptors. Identification of structural fingerprints to increase or decrease in the inhibitory activity was mapped for possible inclusion/exclusion of these fingerprints in the lead optimization process. Challenges in ADME properties of protease inhibitors were also discussed to overcome the problems of oral bioavailability. Further, depending on the modeling results, we have proposed novel as well as potent SARS-CoV-2 Mpro inhibitors.

A search for the flavor-changing neutral-current decay B^{+}→K^{+}νν[over ¯] is performed at the Belle II experiment at the SuperKEKB asymmetric energy electron-positron collider. The data sample corresponds to an integrated luminosity of 63 fb^{-1} collected at the ϒ(4S) resonance and a sample of 9 fb^{-1} collected at an energy 60 MeV below the resonance. Because the measurable decay signature involves only a single charged kaon, a novel measurement approach is used that exploits not only the properties of the B^{+}→K^{+}νν[over ¯] decay, but also the inclusive properties of the other B meson in the ϒ(4S)→BB[over ¯] event, to suppress the background from other B meson decays and light-quark pair production. This inclusive tagging approach offers a higher signal efficiency compared to previous searches. No significant signal is observed. An upper limit on the branching fraction of B^{+}→K^{+}νν[over ¯] of 4.1×10^{-5} is set at the 90% confidence level.

Human meprin β is a Zn2+-containing multidomain metalloprotease enzyme that belongs to the astacin family of the metzincin endopeptidase superfamily. Meprin β, with its diverse tissue expression pattern and wide substrate specificity, plays a significant role in various biological processes, including regulation of IL-6R pathways, lung fibrosis, collagen deposition, cellular migration, neurotoxic amyloid β levels, and inflammation. Again, meprin β is involved in Alzheimer’s disease, hyperkeratosis, glomerulonephritis, diabetic kidney injury, inflammatory bowel disease, and cancer. Despite a crucial role in diverse disease processes, no such promising inhibitors of meprin β are marketed to date. Thus, it is an unmet requirement to find novel promising meprin β inhibitors that hold promise as potential therapeutics. In this study, a series of arylsulfonamide and tertiary amine-based hydroxamate derivatives as meprin β inhibitors has been analyzed through ligand-based and structure-based in silico approaches to pinpoint their structural and physiochemical requirements crucial for exerting higher inhibitory potential. This study identified different crucial structural features such as arylcarboxylic acid, sulfonamide, and arylsulfonamide moieties, as well as hydrogen bond donor and hydrophobicity, inevitable for exerting higher meprin β inhibition, providing valuable insight for their further future development.

We present measurements of the bb production cross section and angular correlations using the DØ detector at the Fermilab Tevatron pp Collider operating at s = 1.8 TeV. The b quark production cross section for |yb|<1.0 and pTb>6 GeV/c is extracted from single muon and dimuon data samples. The results agree in shape with the next-to-leading order QCD calculation of heavy flavor production but are greater than the central values of these predictions. The angular correlations between b and b quarks, measured from the azimuthal opening angle between their decay muons, also agree in shape with the next-to-leading order QCD prediction.

In this Report, QCD results obtained from a study of hadronic event structure in high energy e+e- interactions with the L3 detector are presented. The operation of the LEP collider at many different collision energies from 91 to 209 GeV offers a unique opportunity to test QCD by measuring the energy dependence of different observables. The main results concern the measurement of the strong coupling constant, αs, from hadronic event shapes and the study of effects of soft gluon coherence in charged particle multiplicity and momentum distributions.

Scalar partners of quarks and leptons, predicted in supersymmetric models, are searched for in e^+e^- collisions at centre-of-mass energies between 192GeV and 209GeV at LEP. No evidence for any such particle is found in a data sample of 450 pb^-1. Upper limits on their production cross sections are set and lower limits on their masses are derived in the framework of the Minimal Supersymmetric Standard Model.

We measure the top quark mass m t using t t pairs produced in the DØ detector by √ s = 1.8 TeV pp collisions in a 125 pb -1 exposure at the Fermilab Tevatron.We make a two constraint fit to m t in t t → bW + bW -final states with one W decaying to q q and the other to eν or µν.Events are binned in fit mass versus a measure of probability for events to be signal rather than background.Likelihood fits to the data yield m t = 173.3± 5.6 (stat) ± 6.2 (syst) GeV/c 2 .

We report 2.5 Tb/s (64 /spl times/ 42.7-Gb/s) WDM transmission over 4000 km (forty 100-km spans) of non-zero dispersion-shifted fiber. This capacity /spl times/ distance record of 10 petabit-km/s for 40-Gb/s systems is achieved in a single 53-nm extended L band using return-to-zero differential-phase-shift-keyed modulation, balanced detection, and distributed Raman amplification.

We search for neutral heavy leptons that are isosinglets under the standard SU (2)L gauge group. Such neutral heavy leptons are expected in many extensions of the standard model. Three types of heavy leptons Ne, Nμ, Nτ associated with the three neutrino types ve, vμ, vτ have been directly searched for and no evidence for a signal has been found. We set the limit Br(NSu0 → vℓNℓ) < 3 x 10−5 at the 95% CL for mass range from 3 GeV up to Mz.

The transverse momentum of charged particles produced within the pseudorapidity range \ensuremath{\eta}=-0.36 to +1.0 has been measured in p\ifmmode\bar\else\textasciimacron\fi{}p collisions at \ensuremath{\surd}s =1.8 TeV. The charged-particle multiplicity of each event was measured with a 240-element cylindrical hodoscope system covering the range -3.25&lt;\ensuremath{\eta}&lt;3.25. The average transverse momentum as a function of the average charged-particle density per unit of pseudorapidity is presented. Events are observed with average charged-particle density as high as 32 per unit of pseudorapidity.

The yields and average transverse momenta of pions, kaons, and antiprotons produced at the Fermilab $\overline{p}p$ collider at $\sqrt{s}=300, 540, 1000, \mathrm{and} 1800$ GeV are presented and compared with data from the energies reached at the CERN collider. We also present data on the dependence of average transverse momentum $〈{p}_{t}〉$ and particle ratios as a function of charged particle density $\frac{d{N}_{c}}{d\ensuremath{\eta}}$; data for particle densities as high as six times the average value, corresponding to a Bjorken energy density 6 GeV/${\mathrm{fm}}^{3}$, are reported. These data are relevant to the search for quark-gluon phase of QCD.

We present an improved measurement of CP-violation parameters in B0-->phiK(0)(S), K(+)K(-)K(0)(S), and eta(')K(0)(S) decays based on a 140 fb(-1) data sample collected at the Upsilon(4S) resonance with the Belle detector at the KEKB energy-asymmetric e(+)e(-) collider. One neutral B meson is fully reconstructed in one of the specified decay channels, and the flavor of the accompanying B meson is identified from its decay products. CP-violation parameters for each of the three modes are obtained from the asymmetries in the distributions of the proper-time intervals between the two B decays. We find that the observed CP asymmetry in the B-->phiK(0)(S) decay differs from the standard model (SM) expectation by 3.5 standard deviations, while the other cases are consistent with the SM.

We present a study of jet multiplicities based on 37 000 hadronic Z0 boson decays. From this data we determine the strong coupling constant αs=0.115±0.005 (exp.)−0.010+0.012 (theor.) to second order QCD at √s=91.22GeV.

We present a precise measurement of the standard model $CP$-violation parameter $\mathrm{sin}2{\ensuremath{\phi}}_{1}$, the direct $CP$ violation parameter $|\ensuremath{\lambda}|$, the lifetimes of charged and neutral $B$ mesons and their ratio, and the ${B}^{0}$-${\overline{B}}^{0}$ mixing parameter $\ensuremath{\Delta}{m}_{d}$ based on a sample of $152\ifmmode\times\else\texttimes\fi{}{10}^{6}$ $B\overline{B}$ pairs collected at the $\ensuremath{\Upsilon}(4S)$ resonance with the Belle detector at the KEKB asymmetric-energy ${e}^{+}{e}^{\ensuremath{-}}$ collider. One of two $B$ mesons is fully reconstructed in a $CP$-eigenstate or a flavor-eigenstate decay channel. The flavor of the accompanying $B$ meson is identified from its decay products. From the distributions of the time interval between the two $B$ meson decay points, we obtain $\mathrm{sin}2{\ensuremath{\phi}}_{1}=0.728\ifmmode\pm\else\textpm\fi{}0.056(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.023(\mathrm{syst})$, $|\ensuremath{\lambda}|=1.007\ifmmode\pm\else\textpm\fi{}0.041(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.033(\mathrm{syst})$, ${\ensuremath{\tau}}_{{B}^{0}}=[1.534\ifmmode\pm\else\textpm\fi{}0.008(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.010(\mathrm{syst})]\text{ }\text{ }\mathrm{ps}$, ${\ensuremath{\tau}}_{{B}^{+}}=[1.635\ifmmode\pm\else\textpm\fi{}0.011(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.011(\mathrm{syst})]\text{ }\text{ }\mathrm{ps}$, ${\ensuremath{\tau}}_{{B}^{+}}/{\ensuremath{\tau}}_{{B}^{0}}=1.066\ifmmode\pm\else\textpm\fi{}0.008(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.008(\mathrm{syst})$ and $\ensuremath{\Delta}{m}_{d}=[0.511\ifmmode\pm\else\textpm\fi{}0.005(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.006{(\mathrm{syst})]\text{ }\text{ }\mathrm{ps}}^{\ensuremath{-}1}$. The results for $\mathrm{sin}2{\ensuremath{\phi}}_{1}$ and $|\ensuremath{\lambda}|$ are consistent with the standard model expectations. The significance of the observed deviation from unity in the lifetime ratio exceeds 5 standard deviations.

The yields and the transverse-momentum distributions of pions, kaons, and antiprotons produced in the central region of p¯p collisions at √s =1.8 TeV at the Fermilab Tevatron collider have been measured up to a charged-particle pseudorapidity density of approximately 20. The average transverse momentum 〈pt〉 as a function of 〈dNc/dη〉 for all three types of particles is presented.Received 14 July 1989DOI:https://doi.org/10.1103/PhysRevLett.64.991©1990 American Physical Society

The characteristics of the L3 hadron calorimeter as realized in the observation of hadronic jets and other events from e+e− collisions at LEP are presented and discussed. The pattern-recognition algorithm utilizing the fine granulatiry of the calorimeter is described, and the observed overall resolution of 10.2% for hadron jets from Z decay is reported. The use of the calorimeter in providing information on muon energy losses is also noted.

We present a study of the inclusive production of neutral pions and charged particles from 112 000 hadronic Z0 decays. The measured inclusive momentum distributions can be reproduced by parton shower Monte Carlo programs and also by an analytical QCD calculation. Comparing our results to e+e− data between √s = 9 and 91 GeV, we findfind that the evolution of the spectra with center of mass energy is consistent with the QCD predictions.

We report the results of a search for associated production of charginos and neutralinos using a data set corresponding to an integrated luminosity of 2.3 fb−1 collected with the DØ experiment during Run II of the Tevatron proton–antiproton collider. Final states containing three charged leptons and missing transverse energy are probed for a signal from supersymmetry with four dedicated trilepton event selections. No evidence for a signal is observed, and we set limits on the product of production cross section and leptonic branching fraction. Within minimal supergravity, these limits translate into bounds on m0 and m1/2 that are well beyond existing limits.

We report the results of a search for a heavy neutral gauge boson Z′ decaying into the dielectron final state using data corresponding to an integrated luminosity of 5.4 fb−1 collected by the D0 experiment at the Fermilab Tevatron Collider. No significant excess above the standard model prediction is observed in the dielectron invariant-mass spectrum. We set 95σ(pp¯→Z′)×BR(Z′→ee) depending on the dielectron invariant mass. These cross section limits are used to determine lower mass limits for Z′ bosons in a variety of models. For the sequential standard model Z′ boson a lower mass limit of 1023 GeV is obtained.

We use higher-order quantum chromodynamics calculations to extract the mass of the top quark from the ttbar cross section measured in the lepton+jets channel in ppbar collisions at sqrt(s)=1.96 TeV using 5.3 fb-1 of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron Collider. The extracted top quark pole mass and MSbar mass are compared to the current Tevatron average top quark mass obtained from direct measurements.

We present a model-independent measurement of $t$-channel electroweak production of single top quarks in $\ppbar$ collisions at $\sqrt{s}=1.96\;\rm TeV$. Using $5.4\;\rm fb^{-1}$ of integrated luminosity collected by the D0 detector at the Fermilab Tevatron Collider, and selecting events containing an isolated electron or muon, missing transverse energy and one or two jets originating from the fragmentation of $b$ quarks, we measure a cross section $\sigma({\ppbar}{\rargap}tqb+X) = 2.90 \pm 0.59\;\rm (stat+syst)\; pb$ for a top quark mass of $172.5\;\rm GeV$. The probability of the background to fluctuate and produce a signal as large as the one observed is $1.6\times10^{-8}$, corresponding to a significance of 5.5 standard deviations.

We present a study of the dijet invariant mass spectrum in events with two jets produced in association with a W boson in data corresponding to an integrated luminosity of 4.3 fb^-1 collected with the D0 detector at sqrt{s} =1.96 TeV. We find no evidence for anomalous resonant dijet production and derive upper limits on the production cross section of an anomalous dijet resonance recently reported by the CDF Collaboration, investigating the range of dijet invariant mass from 110 to 170 GeV/c^2. The probability of the D0 data being consistent with the presence of a dijet resonance with 4 pb production cross section at 145 GeV/c^2 is 8x10^-6.

We measure the inclusive single muon charge asymmetry and the like-sign dimuon charge asymmetry in pp collisions using the full data set of 10.4 fb -1 collected with

Drell-Yan lepton pairs produced in the process $p\overline{p}\ensuremath{\rightarrow}{\ensuremath{\ell}}^{+}{\ensuremath{\ell}}^{\ensuremath{-}}+X$ through an intermediate ${\ensuremath{\gamma}}^{*}/Z$ boson have an asymmetry in their angular distribution related to the spontaneous symmetry breaking of the electroweak force and the associated mixing of its neutral gauge bosons. The CDF and D0 experiments have measured the effective-leptonic electroweak mixing parameter ${\mathrm{sin}}^{2}{\ensuremath{\theta}}_{\mathrm{eff}}^{\mathrm{lept}}$ using electron and muon pairs selected from the full Tevatron proton-antiproton data sets collected in 2001-2011, corresponding to $9--10\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of integrated luminosity. The combination of these measurements yields the most precise result from hadron colliders, ${\mathrm{sin}}^{2}{\ensuremath{\theta}}_{\mathrm{eff}}^{\mathrm{lept}}=0.23148\ifmmode\pm\else\textpm\fi{}0.00033$. This result is consistent with, and approaches in precision, the best measurements from electron-positron colliders. The standard model inference of the on-shell electroweak mixing parameter ${\mathrm{sin}}^{2}{\ensuremath{\theta}}_{W}$, or equivalently the $W$-boson mass ${M}_{W}$, using the zfitter software package yields ${\mathrm{sin}}^{2}{\ensuremath{\theta}}_{W}=0.22324\ifmmode\pm\else\textpm\fi{}0.00033$ or equivalently, ${M}_{W}=80.367\ifmmode\pm\else\textpm\fi{}0.017\text{ }\text{ }\mathrm{GeV}/{c}^{2}$.

An angular analysis of the decay B[over ¯]→D^{*}ℓ^{-}ν[over ¯]_{ℓ}, ℓ∈{e,μ}, is reported using the full e^{+}e^{-} collision data set collected by the BABAR experiment at the ϒ(4S) resonance. One B meson from the ϒ(4S)→BB[over ¯] decay is fully reconstructed in a hadronic decay mode, which constrains the kinematics and provides a determination of the neutrino momentum vector. The kinematics of the semileptonic decay is described by the dilepton mass squared, q^{2}, and three angles. The first unbinned fit to the full four-dimensional decay rate in the standard model is performed in the so-called Boyd-Grinstein-Lebed approach, which employs a generic q^{2} parametrization of the underlying form factors based on crossing symmetry, analyticity, and QCD dispersion relations for the amplitudes. A fit using the more model-dependent Caprini-Lellouch-Neubert (CLN) approach is performed as well. Our form factor shapes show deviations from previous fits based on the CLN parametrization. The latest form factors also provide an updated prediction for the branching fraction ratio R(D^{*})≡B(B[over ¯]→D^{*}τ^{-}ν[over ¯]_{τ})/B(B[over ¯]→D^{*}ℓ^{-}ν[over ¯]_{ℓ})=0.253±0.005. Finally, using the well-measured branching fraction for the B[over ¯]→D^{*}ℓ^{-}ν[over ¯]_{ℓ} decay, a value of |V_{cb}|=(38.36±0.90)×10^{-3} is obtained that is consistent with the current world average for exclusive B[over ¯]→D^{(*)}ℓ^{-}ν[over ¯]_{ℓ} decays and remains in tension with the determination from inclusive semileptonic B decays to final states with charm.

Theories beyond the standard model often predict the existence of an additional neutral boson, the $Z^{\prime}$. Using data collected by the Belle II experiment during 2018 at the SuperKEKB collider, we perform the first searches for the invisible decay of a $Z^{\prime}$ in the process $e^+ e^- \to \mu^+ \mu^- Z^{\prime}$ and of a lepton-flavor-violating $Z^{\prime}$ in $e^+ e^- \to e^{\pm} \mu^{\mp} Z^{\prime}$. We do not find any excess of events and set 90\% credibility level upper limits on the cross sections of these processes. We translate the former, in the framework of an $L_{\mu}-L_{\tau}$ theory, into upper limits on the $Z^{\prime}$ coupling constant at the level of $5 \times 10^{-2}$ -- $1$ $M_{Z^\prime}\leq 6$ GeV/$c^2$.

The fascinating similarity between the SARS-CoV and SARS-CoV-2, inspires scientific community to investigate deeper into the SARS-CoV proteases such as main protease (Mpro) and papain-like protease (PLpro) and their inhibitors for the discovery of SARS-CoV-2 protease inhibitors. Because of the similarity in the proteases of these two corona viruses, there is a greater chance for the previous SARS-CoV Mpro and PLpro inhibitors to provide effective results against SARS-CoV-2. In this context, the molecular fragments from the SARS-CoV protease inhibitors through the fragment-based drug design and discovery technique can be useful guidance for COVID-19 drug discovery. Here, we have focused on the structure-activity relationship studies of previous SARS-CoV protease inhibitors and discussed about crucial fragments generated from previous SARS-CoV protease inhibitors important for the lead optimization of SARS-CoV-2 protease inhibitors. This study surely offers different strategic options of lead optimization to the medicinal chemists to discover effective anti-viral agent against the devastating disease, COVID-19.

Among various matrix metalloproteinases (MMPs), MMPs having medium-size S1' pockets are established as promising biomolecular targets for executing crucial roles in cancer, cardiovascular diseases, and neurodegenerative diseases. However, no such MMP inhibitors (MMPIs) are available to date as drug candidates despite a lot of continuous research work for more than three decades. Due to a high degree of structural resemblance among these MMPs, designing selective MMPIs is quite challenging. However, the variability and uniqueness of the S1' pockets of these MMPs make them promising targets for designing selective MMPIs. In this perspective, the overall structural aspects of medium-size S1' pocket MMPs including the unique binding patterns of enzyme-inhibitor interactions have been discussed in detail to acquire knowledge regarding selective inhibitor designing. This overall knowledge will surely be a curtain raiser for the designing of selective MMPIs as drug candidates in the future.

We report a measurement of the top quark mass using six candidate events for the process $p\overline{p}\ensuremath{\rightarrow}t\overline{t}+\stackrel{\ensuremath{\rightarrow}}{X}{l}^{+}\ensuremath{\nu}{\mathrm{bl}}^{\ensuremath{-}}\overline{\ensuremath{\nu}}\overline{b}+X$, observed in the D0 experiment at the Fermilab $p\overline{p}$ collider. Using maximum likelihood fits to the dynamics of the decays, we measure a mass for the top quark of ${m}_{t}=168.4\ifmmode\pm\else\textpm\fi{}12.3(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}3.6(\mathrm{syst}) \mathrm{Gev}$. We combine this result with our previous measurement in the $t\overline{t}\ensuremath{\rightarrow}l+\mathrm{jets}$ channel to obtain ${m}_{t}=172.1\ifmmode\pm\else\textpm\fi{}7.1 \mathrm{GeV}$ as the best value of the mass of the top quark measured by D0.

We have made a precise measurement of the cross section for e+e−→Z0→hadrons with the L3 detector at LEP, covering the s range from 88.28 to 95.04 GeV. From a fit to the Z0 mass, total width, and the hadronic cross section to be MZ0=91.160 ± 0.024 (experiment) ±0.030(LEP) GeV, ΓZ0=2.539±0.054 GeV, and σh(MZ0)=29.5±0.7 nb. We also used the fit to the Z0 peak cross section and the width todetermine Γinvisible=0.548±0.029 GeV, which corresponds to 3.29±0.17 species of light neutrinos. The possibility of four or more neutrino flavors is thus ruled out at the 4σ confidence level.

Single top production in e+e- annihilations is searched for in data collected by the L3 detector at centre-of-mass energies from 189 to 209 GeV, corresponding to a total integrated luminosity of 634 pb-1. Investigating hadronic and semileptonic top decays, no evidence of single top production at LEP is obtained and upper limits on the single top cross section as a function of the centre-of-mass energy are derived. Limits on possible anomalous couplings, as well as on the scale of contact interactions responsible for single top production are determined.

We have studied the reactionse + e −→hadrons,e + e −, μ+ μ− and τ+ τ−, in the energy range 88.2 $$ \leqq \sqrt s \leqq 94.2$$ GeV. A total luminosity of 5.5 pb−1, corresponding to approximately 115000 hadronic and 10000 leptonicZ 0 decays, has been recorded with the L3 detector. From a simultaneous fit to all of our measured cross section data, we obtain assuming lepton universality: $$\begin{gathered} M_z = 91.181 \pm 0.010 \pm 0.02 (LEP) GeV, \hfill \\ \Gamma _z = 2501 \pm 17 MeV, \hfill \\ \Gamma _{had} = 1742 \pm 19 MeV, \Gamma _t = 83.6 \pm 0.8 MeV. \hfill \\ \end{gathered}$$ If we do not assume lepton universality, we obtain for the partial decay widths of theZ 0 intoe + e − μ+ μ− and τ+ τ−: $$\begin{gathered} \Gamma _e = 83.3 \pm 1.1 MeV, \Gamma _\mu = 84.5 \pm 2.0 MeV, \hfill \\ \Gamma _\tau = 84.0 \pm 2.7 MeV. \hfill \\ \end{gathered}$$ From the measured ratio of the invisible and the leptonic decay widths of theZ 0, we determine the number of light neutrino species to beN v =3.05±0.10. We include our measurements of the forward-backward asymmetry for the leptonic channels in a fit to determine the vector and axial-vector neutral current coupling constants of charged leptons to theZ 0. We obtain $$\bar g_V = - 0.046_{ - 0.012}^{ + 0.015}$$ and $$\bar g_A = - 0.500 \pm 0.003$$ . In the framework of the Standard Model, we estimate the top quark mass to bem t =193 −69 +52 ±16 (Higgs) GeV, and we derive a value for the weak mixing angle of sin2θ W =1−(M W /M Z )2=0.222 ± 0.008, corresponding to an effective weak mixing angle of $$\sin ^2 \bar \theta _W = 0.2315 \pm 0.0025$$ .

The inclusive cross sections for forward D meson production at s=26 GeV in π−p interactions have been measured to be: σ(π−p→D0/D0+X)xF>0 = (10.1±2.2)μb, σ(π−p→D±+X)xF>0 = (5.7±1.6)μb. The distribution in xF for all D and for xF>0 has the form dσ/dxF=107−37+39(1−xF)7.5−1.7+2.5+5.4−3.8+6.0(1−xF)0.7−0.71.0μ b, with evidence for leading D production. The pT2 distribution is exponential with slope parameter [−1.18−0.16+0.18](GeV/ c)−2. The data are compared with predictions from first-order quark/gluon fusion calculations.

A study of the properties of charm particles produced in 400 GeV/cpp interactions is reported. The experiment was performed using the high resolution hydrogen bubble chamber LEBC in association with the European Hybrid Spectrometer at the CERN SPS. Details of the experimental set-up and operational procedures are given and the methods to extract samples of charm decays are discussed. Results are presented on the intrinsic properties of charm particles (masses, lifetimes, decay modes and branching ratios), adding, whenever appropriate, the relevant information obtained in a similar study made with 360 GeV/cπ − p interactions. The hadroproduction properties of charm states (total and differential cross sections, correlations) are presented and discussed in the context of current QCD inspired phenomenology.

We present a measurement of the electron charge asymmetry in pp[over ]-->W+X-->enu+X events at a center of mass energy of 1.96 TeV using 0.75 fb(-1) of data collected with the D0 detector at the Fermilab Tevatron Collider. The asymmetry is measured as a function of the electron transverse momentum and pseudorapidity in the interval (-3.2, 3.2) and is compared with expectations from next-to-leading order calculations in perturbative quantum chromodynamics. These measurements will allow more accurate determinations of the proton parton distribution functions.

We present the first experimental discrimination between the 2e/3 and 4e/3 top quark electric charge scenarios, using top quark pairs (tt¯) produced in pp¯ collisions at s=1.96 TeV by the Fermilab Tevatron Collider. We use 370 pb−1 of data collected by the D0 experiment and select events with at least one high transverse momentum electron or muon, high transverse energy imbalance, and four or more jets. We discriminate between b- and b¯-quark jets by using the charge and momenta of tracks within the jet cones. The data are consistent with the expected electric charge, |q|=2e/3. We exclude, at the 92% C.L., that the sample is solely due to the production of exotic quark pairs QQ¯ with |q|=4e/3. We place an upper limit on the fraction of QQ¯ pairs ρ<0.80 at the 90% C.L.Received 18 August 2006DOI:https://doi.org/10.1103/PhysRevLett.98.041801©2007 American Physical Society

We present a search for the pair production of scalar top quarks, t˜, using 995 pb−1 of data collected in pp¯ collisions with the DØ detector at the Fermilab Tevatron Collider at s=1.96TeV. Both scalar top quarks are assumed to decay into a charm quark and a neutralino (χ˜10), where χ˜10 is the lightest supersymmetric particle. This leads to a final state with two acoplanar charm jets and missing transverse energy. We find the yield of such events to be consistent with the standard model expectation, and exclude sets of t˜ and χ˜10 masses at the 95% C.L. that substantially extend the domain excluded by previous searches.

We search for long-lived charged massive particles using $1.1\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data collected by the D0 detector at the Fermilab Tevatron $p\overline{p}$ Collider. Time-of-flight information is used to search for pair produced long-lived tau sleptons, gauginolike charginos, and Higgsino-like charginos. We find no evidence of a signal and set 95% C.L. cross section upper limits for staus, which vary from 0.31 to 0.04 pb for stau masses between 60 and 300 GeV. We also set lower mass limits of 206 GeV (171 GeV) for pair produced charged gauginos (Higgsinos).

We search for the production of a heavy W′ gauge boson that decays to third generation quarks in 0.9 fb−1 of pp¯ collisions at s=1.96 TeV, collected with the D0 detector at the Fermilab Tevatron collider. We find no significant excess in the final-state invariant mass distribution and set upper limits on the production cross section times branching fraction. For a left-handed W′ boson with SM couplings, we set a lower mass limit of 731 GeV. For right-handed W′ bosons, we set lower mass limits of 739 GeV if the W′ boson decays to both leptons and quarks and 768 GeV if the W′ boson decays only to quarks. We also set limits on the coupling of the W′ boson to fermions as a function of its mass.Received 21 March 2008DOI:https://doi.org/10.1103/PhysRevLett.100.211803©2008 American Physical Society

The D0 Collaboration reports direct evidence for electroweak production of single top quarks through the t-channel exchange of a virtual W boson. This is the first analysis to isolate an individual single top quark production channel. We select events containing an isolated electron or muon, missing transverse energy, and two, three or four jets from 2.3 fb−1 of pp¯ collisions at the Fermilab Tevatron Collider. One or two of the jets are identified as containing a b hadron. We combine three multivariate techniques optimized for the t-channel process to measure the t- and s-channel cross sections simultaneously. We measure cross sections of 3.14−0.80+0.94pb for the t-channel and 1.05±0.81pb for the s-channel. The measured t-channel result is found to have a significance of 4.8 standard deviations and is consistent with the standard model prediction.

We report on a first search for production of the lightest neutral $CP$-even Higgs boson ($h$) in the next-to-minimal supersymmetric standard model, where $h$ decays to a pair of neutral pseudoscalar Higgs bosons ($a$), using $4.2\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data recorded with the D0 detector at Fermilab. The $a$ bosons are required to either both decay to ${\ensuremath{\mu}}^{+}{\ensuremath{\mu}}^{\ensuremath{-}}$ or one to ${\ensuremath{\mu}}^{+}{\ensuremath{\mu}}^{\ensuremath{-}}$ and the other to ${\ensuremath{\tau}}^{+}{\ensuremath{\tau}}^{\ensuremath{-}}$. No significant signal is observed, and we set limits on its production as functions of ${M}_{a}$ and ${M}_{h}$.

We present a new measurement of the Z/γ∗ transverse momentum distribution in the range 0–330 GeV, in proton–antiproton collisions at s=1.96TeV. The measurement uses 0.97 fb−1 of integrated luminosity recorded by the D0 experiment and is the first using the Z/γ∗→μ+μ−+X channel at this center-of-mass energy. This is also the first measurement of the Z/γ∗ transverse momentum distribution that presents the result at the level of particles entering the detector, minimizing dependence on theoretical models. As any momentum of the Z/γ∗ in the plane transverse to the incoming beams must be balanced by some recoiling system, primarily the result of QCD radiation in the initial state, this variable is an excellent probe of the underlying process. Tests of the predictions of QCD calculations and current event generators show they have varied success in describing the data. Using this measurement as an input to theoretical predictions will allow for a better description of hadron collider data and hence it will increase experimental sensitivity to rare signals.

We present a measurement of the average value of a new observable at hadron colliders that is sensitive to QCD dynamics and to the strong coupling constant, while being only weakly sensitive to parton distribution functions. The observable measures the angular correlations of jets and is defined as the number of neighboring jets above a given transverse momentum threshold which accompany a given jet within a given distance Delta-R in the plane of rapidity and azimuthal angle. The ensemble average over all jets in an inclusive jet sample is measured and the results are presented as a function of transverse momentum of the inclusive jets, in different regions of Delta-R and for different transverse momentum requirements for the neighboring jets. The measurement is based on a data set corresponding to an integrated luminosity of 0.7 fb-1 collected with the D0 detector at the Fermilab Tevatron Collider in pp-bar collisions at sqrt(s)=1.96 The results are well described by a perturbative QCD calculation in next-to-leading order in the strong coupling constant, corrected for non-perturbative effects. From these results, we extract the strong coupling and test the QCD predictions for its running over a range of momentum transfers of 50-400 GeV.

Using data corresponding to an integrated luminosity of 1.3 fb^-1, we observe a narrow mass state decaying into Upsilon(1S)+gamma, where the Upsilon(1S) meson is detected by its decay into a pair of oppositely charged muons, and the photon is identified through its conversion into an electron-positron pair. The significance of this observation is 5.6 standard deviations. The mass of the state is centered at 10.551 \pm 0.014 (stat.) \pm 0.017 (syst.) GeV/c^2, which is consistent with that of the state recently observed by the ATLAS Collaboration.

The production of top quark-antiquark pair events in $p\bar{p}$ collisions at $\sqrt{s}=1.96$ TeV is studied as a function of the transverse momentum and absolute value of the rapidity of the top quarks as well as of the invariant mass of the $t\bar{t}$ pair. We select events containing an isolated lepton, a large imbalance in transverse momentum, and four or more jets with at least one jet identified to originate from a $b$ quark. The data sample corresponds to 9.7 fb$^{-1}$ of integrated luminosity recorded with the D0 detector during Run II of the Fermilab Tevatron Collider. Observed differential cross sections are consistent with standard model predictions.

The discovery of the Higgs boson in 2012, by the ATLAS and CMS experiments, was a success achieved with only a percent of the entire dataset foreseen for the LHC. It opened a landscape of possibilities in the study of Higgs boson properties, Electroweak Symmetry breaking and the Standard Model in general, as well as new avenues in probing new physics beyond the Standard Model. Six years after the discovery, with a conspicuously larger dataset collected during LHC Run 2 at a 13 TeV centre-of-mass energy, the theory and experimental particle physics communities have started a meticulous exploration of the potential for precision measurements of its properties. This includes studies of Higgs boson production and decays processes, the search for rare decays and production modes, high energy observables, and searches for an extended electroweak symmetry breaking sector. This report summarises the potential reach and opportunities in Higgs physics during the High Luminosity phase of the LHC, with an expected dataset of pp collisions at 14 TeV, corresponding to an integrated luminosity of 3 ab$^{-1}$. These studies are performed in light of the most recent analyses from LHC collaborations and the latest theoretical developments. The potential of an LHC upgrade, colliding protons at a centre-of-mass energy of 27 TeV and producing a dataset corresponding to an integrated luminosity of 15 ab$^{-1}$, is also discussed.

Abstract From April to July 2018, a data sample at the peak energy of the <?CDATA $ \varUpsilon \left( {4{\rm{S}}} \right)$?> resonance was collected with the Belle II detector at the SuperKEKB electron-positron collider. This is the first data sample of the Belle II experiment. Using Bhabha and digamma events, we measure the integrated luminosity of the data sample to be ( <?CDATA $ 496.3 \pm 0.3 \pm 3.0)\;{\rm pb}^{-1}$?> , where the first uncertainty is statistical and the second is systematic. This work provides a basis for future luminosity measurements at Belle II.

We study the processes $\gamma \gamma \to \eta_c \to \eta' K^+ K^-$, $\eta' \pi^+ \pi^-$, and $\eta \pi^+ \pi^-$ using a data sample of 519 $fb^{-1}$ recorded with the BaBar detector operating at the SLAC PEP-II asymmetric-energy $e^+e^-$ collider at center-of-mass energies at and near the $\Upsilon(nS)$ ($n = 2,3,4$) resonances. This is the first observation of the decay $\eta_c \to \eta' K^+ K^-$ and we measure the branching fraction $\Gamma(\eta_c \to \eta' K^+ K^-)/(\Gamma(\eta_c \to \eta' \pi^+ \pi^-)=0.644\pm 0.039_{\rm stat}\pm 0.032_{\rm sys}$. Significant interference is observed between $\gamma \gamma \to \eta_c\to \eta \pi^+ \pi^-$ and the non-resonant two-photon process $\gamma \gamma \to \eta \pi^+ \pi^-$. A Dalitz plot analysis is performed of $\eta_c$ decays to $\eta' K^+ K^-$, $\eta' \pi^+ \pi^-$, and $\eta \pi^+ \pi^-$. Combined with our previous analysis of $\eta_c \to K \bar K \pi$, we measure the $K^*_0(1430)$ parameters and the ratio between its $\eta' K$ and $\pi K$ couplings. The decay $\eta_c \to \eta' \pi^+ \pi^-$ is dominated by the $f_0(2100)$ resonance, also observed in $J/\psi$ radiative decays. A new $a_0(1700) \to \eta \pi$ resonance is observed in the $\eta_c \to \eta \pi^+ \pi^-$ channel. We also compare $\eta_c$ decays to $\eta$ and $\eta'$ final states in association with scalar mesons as they relate to the identification of the scalar glueball.

Due to COVID-19, the whole world is undergoing a devastating situation, but treatment with no such drug candidates still has been established exclusively. In that context, 69 diverse chemicals with potential SARS-CoV-2 3CLpro inhibitory property were taken into consideration for building different internally and externally validated linear (SW-MLR and GA-MLR), non-linear (ANN and SVM) QSAR, and HQSAR models to identify important structural and physicochemical characters required for SARS-CoV-2 3CLpro inhibition. Importantly, 2-oxopyrrolidinyl methyl and benzylester functions, and methylene (hydroxy) sulphonic acid warhead group, were crucial for retaining higher SARS-CoV-2 3CLpro inhibition. These GA-MLR and HQSAR models were also applied to predict some already repurposed drugs. As per the GA-MLR model, curcumin, ribavirin, saquinavir, sepimostat, and remdesivir were found to be the potent ones, whereas according to the HQSAR model, lurasidone, saquinavir, lopinavir, elbasvir, and paritaprevir were the highly effective SARS-CoV-2 3CLpro inhibitors. The binding modes of those repurposed drugs were also justified by the molecular docking, molecular dynamics (MD) simulation, and binding energy calculations conducted by several groups of researchers. This current work, therefore, may be able to find out important structural parameters to accelerate the COVID-19 drug discovery processes in the future.

Abstract We report on new flavor tagging algorithms developed to determine the quark-flavor content of bottom ( "Image missing"<!-- image only, no MathML or LaTex -->) mesons at Belle II. The algorithms provide essential inputs for measurements of quark-flavor mixing and charge-parity violation. We validate and evaluate the performance of the algorithms using hadronic "Image missing"<!-- image only, no MathML or LaTex --> decays with flavor-specific final states reconstructed in a data set corresponding to an integrated luminosity of 62.8 fb $$^{-1}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msup> <mml:mrow /> <mml:mrow> <mml:mo>-</mml:mo> <mml:mn>1</mml:mn> </mml:mrow> </mml:msup> </mml:math> , collected at the "Equation missing"<!-- image only, no MathML or LaTex --> resonance with the Belle II detector at the SuperKEKB collider. We measure the total effective tagging efficiency to be $$\begin{aligned} \varepsilon _\mathrm{eff} = \big (30.0 \pm 1.2(\text {stat}) \pm 0.4(\text {syst})\big )\% \end{aligned}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mtable> <mml:mtr> <mml:mtd> <mml:mrow> <mml:msub> <mml:mi>ε</mml:mi> <mml:mi>eff</mml:mi> </mml:msub> <mml:mo>=</mml:mo> <mml:mrow> <mml:mo>(</mml:mo> </mml:mrow> <mml:mn>30.0</mml:mn> <mml:mo>±</mml:mo> <mml:mn>1.2</mml:mn> <mml:mrow> <mml:mo>(</mml:mo> <mml:mtext>stat</mml:mtext> <mml:mo>)</mml:mo> </mml:mrow> <mml:mo>±</mml:mo> <mml:mn>0.4</mml:mn> <mml:mrow> <mml:mo>(</mml:mo> <mml:mtext>syst</mml:mtext> <mml:mo>)</mml:mo> </mml:mrow> <mml:mrow> <mml:mo>)</mml:mo> </mml:mrow> <mml:mo>%</mml:mo> </mml:mrow> </mml:mtd> </mml:mtr> </mml:mtable> </mml:mrow> </mml:math> for a category-based algorithm and $$\begin{aligned} \varepsilon _\mathrm{eff} = \big (28.8 \pm 1.2(\text {stat}) \pm 0.4(\text {syst})\big )\% \end{aligned}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mtable> <mml:mtr> <mml:mtd> <mml:mrow> <mml:msub> <mml:mi>ε</mml:mi> <mml:mi>eff</mml:mi> </mml:msub> <mml:mo>=</mml:mo> <mml:mrow> <mml:mo>(</mml:mo> </mml:mrow> <mml:mn>28.8</mml:mn> <mml:mo>±</mml:mo> <mml:mn>1.2</mml:mn> <mml:mrow> <mml:mo>(</mml:mo> <mml:mtext>stat</mml:mtext> <mml:mo>)</mml:mo> </mml:mrow> <mml:mo>±</mml:mo> <mml:mn>0.4</mml:mn> <mml:mrow> <mml:mo>(</mml:mo> <mml:mtext>syst</mml:mtext> <mml:mo>)</mml:mo> </mml:mrow> <mml:mrow> <mml:mo>)</mml:mo> </mml:mrow> <mml:mo>%</mml:mo> </mml:mrow> </mml:mtd> </mml:mtr> </mml:mtable> </mml:mrow> </mml:math> for a deep-learning-based algorithm.

In a search for the Standard Model Higgs boson, carried out on 212.5 pb-1 of data collected by the L3 detector at the highest LEP centre-of-mass energies, including 116.5 pb-1 above root(s) = 206GeV, an excess of candidates for the process e+e- -> Z* -> HZ is found for Higgs masses near 114.5GeV. We present an analysis of our data and the characteristics of our strongest candidates.

We present a measurement of the $t\overline{t}$ production cross section in $p\overline{p}$ collisions at $\sqrt{s}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}1.8\mathrm{TeV}$ by the D0 experiment at the Fermilab Tevatron. The measurement is based on data from an integrated luminosity of approximately $125{\mathrm{pb}}^{\ensuremath{-}1}$ accumulated during the 1992--1996 collider run. We observe 39 $t\overline{t}$ candidate events in the dilepton and $\mathrm{lepton}+\mathrm{jets}$ decay channels with an expected background of $13.7\ifmmode\pm\else\textpm\fi{}2.2$ events. For a top quark mass of $173.3\mathrm{GeV}{/c}^{2}$, we measure the $t\overline{t}$ production cross section to be $5.5\ifmmode\pm\else\textpm\fi{}1.8\mathrm{pb}$.

Bottom-quark production in $\overline{p}p$ collisions at $\sqrt{s}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}1.8\mathrm{TeV}$ is studied with $5{\mathrm{pb}}^{\ensuremath{-}1}$ of data collected in 1995 by the D0 detector at the Fermilab Tevatron Collider. The differential production cross section for $b$ jets in the central rapidity region ( $|{y}^{b}|&lt;1$) as a function of jet transverse energy is extracted from a muon-tagged jet sample. Within experimental and theoretical uncertainties, D0 results are found to be higher than, but compatible with, next-to-leading-order QCD predictions.

We report a search for effects of large extra spatial dimensions in pp collisions at a center-of-mass energy of 1.8 TeV with the D0 detector, using events containing a pair of electrons or photons. The data are in good agreement with the expected background and do not exhibit evidence for large extra dimensions. We set the most restrictive lower limits to date, at the 95% C.L. on the effective Planck scale between 1.0 and 1.4 TeV for several formalisms and numbers of extra dimensions.

By optimising the detector threshold and using an optical reservoir channel, error-free transmission of 32 × 2.5 Gbit/s DWDM channels has been obtained over 125 km of AllWave™ fibre using semiconductor optical amplifiers.

We report on a search for the first generation heavy neutrino that is an isosinglet under the standard SU(2)_L gauge group. The data collected with the L3 detector at center-of-mass energies between 130 GeV and 208 GeV are used.The decay channel N_e --> eW is investigated and no evidence is found for a heavy neutrino, N_e, in a mass range between 80 GeV and 205 GeV. Upper limits on the mixing parameter between the heavy and light neutrino are derived.

We present a measurement of the Drell-Yan cross section at high dielectron invariant mass using $120\mathrm{pb}{}^{\ensuremath{-}1}$ of data collected in $p\overline{p}$ collisions at $\sqrt{s}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}1.8\mathrm{TeV}$ by the D0 Collaboration during 1992--1996. No deviation from standard model expectations is observed. We use the data to set limits on the quark-electron compositeness scale. The $95%$ confidence level lower limits on the compositeness scale vary between 3.3 and 6.1 TeV depending on the assumed form of the effective contact interaction.

Using the D0 detector at the 1.8 TeV $\overline{p}p$ Fermilab Tevatron collider, we have measured the inclusive dijet mass spectrum in the central pseudorapidity region $|{\ensuremath{\eta}}_{\mathrm{jet}}|&lt;1.0$ for dijet masses greater than $200\mathrm{GeV}{/c}^{2}$. We have also measured the ratio of spectra $\ensuremath{\sigma}(|{\ensuremath{\eta}}_{\mathrm{jet}}|&lt;0.5)/\ensuremath{\sigma}(0.5&lt;|{\ensuremath{\eta}}_{\mathrm{jet}}|&lt;1.0)$. The order ${\ensuremath{\alpha}}_{s}^{3}$ quantum chromodynamics predictions are in good agreement with the data and we rule out models of quark compositeness with a contact interaction scale $&lt;2.4\mathrm{TeV}$ at the $95%$ confidence level.

The ηπ+π− final state in two-photon collisions is studied with the L3 detector at LEP, at centre-of-mass energies from 183 to 209 GeV with an integrated luminosity of 664.6 pb−1. The f1(1285) meson is observed and the Q2 dependence of its production is compared to different form factor models. The γγ-coupling parameter Γγγ is found to be 3.5±0.6(stat.)±0.5(sys.) keV. The branching fraction Γ(f1(1285)→a0π)/Γ(f1(1285)→ηππ) is also measured.

We present a search for large extra dimensions (ED) in pp collisions at a center-of-mass energy of 1.8 TeV using data collected by the DØ detector at the Fermilab Tevatron in 1994-1996. Data corresponding to 78.8+/-3.9 pb(-1) are examined for events with large missing transverse energy, one high-p(T) jet, and no isolated muons. There is no excess observed beyond expectation from the standard model, and we place lower limits on the fundamental Planck scale of 1.0 and 0.6 TeV for 2 and 7 ED, respectively.

We have measured π+π− and K+K− production in two-photon collisions using 87.7fb−1 of data collected with the Belle detector at the asymmetric energy e+e− collider KEKB. The cross sections are measured to high precision in the two-photon center-of-mass energy (W) range between 2.4GeV<W<4.1GeV and angular region |cosθ∗|<0.6. The cross section ratio σ(γγ→K+K−)/σ(γγ→π+π−) is measured to be 0.89±0.04(stat.)±0.15(syst.) in the range of 3.0GeV<W<4.1GeV, where the ratio is energy-independent. We observe a sin−4θ∗ behavior of the cross section in the same W range. Production of χc0 and χc2 mesons is observed in both γγ→π+π− and γγ→K+K− modes.

A study of the properties of charm particles produced in 360 GeV/c π- p interactions is reported. The experiment was performed using the high resolution hydrogen bubble chamber LEBC in association with the European Hybrid Spectrometer at the CERN SPS. Details of the exposure and operation of the spectrometer are given and the methods used to extract the charm data are presented. The essential physics results on the decay properties (lifetime, branching ratios) as well as on the hadroproduction properties (cross sections forD, $$\bar D$$ ,F, Λ c ,D, correlations between charm particles) are given.