Stereochemistry (Page 1)

The <i>α</i>/<i>β</i> hydrolase fold

The relationship between proton-proton NMR coupling constants and substituent electronegativities—I

Structure of the αβ tubulin dimer by electron crystallography

PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

An intermediate neglect of differential overlap technique for spectroscopy: Pyrrole and the azines

X-ray structure analysis of a membrane protein complex

Catalytic Functionalization of C(sp²)H and C(sp³)H Bonds by Using Bidentate Directing Groups

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

Discovering High-Affinity Ligands for Proteins: SAR by NMR

3D structure of Alzheimer's amyloid-β(1–42) fibrils

The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

A semiempirical free energy force field with charge‐based desolvation

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE

Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate

Cation-π interactions in structural biology

Updated Functional Classification of β-Lactamases

A Homochiral Porous Metal−Organic Framework for Highly Enantioselective Heterogeneous Asymmetric Catalysis

Frustrated Lewis Pairs: Metal‐free Hydrogen Activation and More

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

All ras proteins are polyisoprenylated but only some are palmitoylated

A Rationale for the Large Breathing of the Porous Aluminum Terephthalate (MIL‐53) Upon Hydration

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Primary structure effects on peptide group hydrogen exchange

Structures and mechanisms of glycosyl hydrolases

A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

A One-Year Trial of Lamivudine for Chronic Hepatitis B

Asymmetric Catalysis by Chiral Hydrogen‐Bond Donors

<i>para</i>-Bridged Symmetrical Pillar[5]arenes: Their Lewis Acid Catalyzed Synthesis and Host–Guest Property

Molecular Similarity Indices in a Comparative Analysis (CoMSIA) of Drug Molecules to Correlate and Predict Their Biological Activity

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease

The 2.6 Angstrom Crystal Structure of a Human A _2A Adenosine Receptor Bound to an Antagonist

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Carbon nanotube intramolecular junctions

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

Giving According to GARP: An Experimental Test of the Consistency of Preferences for Altruism

Gaussian-3 theory using density functional geometries and zero-point energies

Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

High-level semi-synthetic production of the potent antimalarial artemisinin

Novel Procedure for Modeling Ligand/Receptor Induced Fit Effects

Glycosyltransferases: Structures, Functions, and Mechanisms

Turns in Peptides and Proteins

Refined Structure of the Nicotinic Acetylcholine Receptor at 4Å Resolution

Some observations upon a new inhibitor of monoamine oxidase in brain tissue

New sensing mechanisms for design of fluorescent chemosensors emerging in recent years

Peptide Folding: When Simulation Meets Experiment

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Proton NMR chemical shifts and coupling constants for brain metabolites

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Glutathione and its role in cellular functions

The Aryl Hydrocarbon Receptor Complex

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

Eine neue Methode zur Synthese von Peptiden: Aktivierung der Carboxylgruppe mit Dicyclohexylcarbodiimid unter Zusatz von 1‐Hydroxy‐benzotriazolen

Rules for optimization of biocatalysis in organic solvents

Natural products in drug discovery

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

586. Olefin co-ordination compounds. Part III. Infra-red spectra and structure: attempted preparation of acetylene complexes

Coordinating properties of the amide bond. Stability and structure of metal ion complexes of peptides and related ligands

Amide bond formation and peptide coupling

LigandScout: 3-D Pharmacophores Derived from Protein-Bound Ligands and Their Use as Virtual Screening Filters

Crystal Structure of the 20<i>S</i>Proteasome from the Archaeon<i>T. acidophilum</i>at 3.4 Å Resolution

Biological effects of resveratrol

Opioids excite dopamine neurons by hyperpolarization of local interneurons

Structural and sequence-based classification of glycoside hydrolases

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

A unified view of ligand-protected gold clusters as superatom complexes

Tertiary templates for proteins

1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity

Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units

Halogen bonds in biological molecules

Elucidation of cross relaxation in liquids by two-dimensional N.M.R. spectroscopy

Fluids with highly directional attractive forces. III. Multiple attraction sites

Contemporary Issues in Electron Transfer Research

Protein NMR Structure Determination with Automated NOE Assignment Using the New Software CANDID and the Torsion Angle Dynamics Algorithm DYANA

Frustrated Lewis Pair Chemistry: Development and Perspectives

A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants

Hardness, softness, and the fukui function in the electronic theory of metals and catalysis.

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

General synthesis and definitive structural identification of MN4C4 single-atom catalysts with tunable electrocatalytic activities

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

Structure of Bcl-x _L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

A Critical Assessment of Docking Programs and Scoring Functions

Enantioselective aldol condensations. 2. Erythro-selective chiral aldol condensations via boron enolates

Single-Molecule Enzymatic Dynamics

Epik: a software program for pK a prediction and protonation state generation for drug-like molecules