Medicinal chemistry (Page 1)

Radical Reactions of C ₆₀

FLUORIDE-INDUCED 1,2-ELIMINATION OF<i>O</i>-TRIMETHYLSILYLPHENYL TRIFLATE TO BENZYNE UNDER MILD CONDITIONS

Torsional strain involving partial bonds. The stereochemistry of the lithium aluminium hydride reduction of some simple open-chain ketones

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp² and sp³ Carbon−Hydrogen Bonds

Understanding the Reactivity of Captodative Ethylenes in Polar Cycloaddition Reactions. A Theoretical Study

Modified (NHC)Pd(allyl)Cl (NHC = <i>N</i>-Heterocyclic Carbene) Complexes for Room-Temperature Suzuki−Miyaura and Buchwald−Hartwig Reactions

Facile Splitting of Hydrogen and Ammonia by Nucleophilic Activation at a Single Carbon Center

A Proficient Enzyme

Tertiary Phosphane/Tetrachloromethane, a Versatile Reagent for Chlorination, Dehydration, and PN Linkage

A LiCl-Mediated Br/Mg Exchange Reaction for the Preparation of Functionalized Aryl- and Heteroarylmagnesium Compounds from Organic Bromides

Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids

Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry

Efficient Activation of Aromatic C-H Bonds for Addition to C-C Multiple Bonds

Asymmetric Ylide Reactions: Epoxidation, Cyclopropanation, Aziridination, Olefination, and Rearrangement

The thiobarbituric acid reaction and the autoxidations of polyunsaturated fatty acid methyl esters

A General and Efficient Copper Catalyst for the Amidation of Aryl Halides

Nature of Urea−Fluoride Interaction: Incipient and Definitive Proton Transfer

Catalytic Intermolecular Direct Arylation of Perfluorobenzenes

1,3-Dimethyl-4-imidazolinyliden-(2)-pentacarbonylchrom ein neuer übergangsmetall-carben-komplex

The Metal−Ligand Bifunctional Catalysis: A Theoretical Study on the Ruthenium(II)-Catalyzed Hydrogen Transfer between Alcohols and Carbonyl Compounds

Radiation Damage in Organic Crystals. II. Electron Spin Resonance of (CO2H)CH2CH(CO2H) in β-Succinic Acid

The Cucurbit[<i>n</i>]uril Family: Prime Components for Self-Sorting Systems

.sigma.-Bond metathesis for carbon-hydrogen bonds of hydrocarbons and Sc-R (R = H, alkyl, aryl) bonds of permethylscandocene derivatives. Evidence for noninvolvement of the .pi. system in electrophilic activation of aromatic and vinylic C-H bonds

On Approaching the Limit of Molecular Magnetic Anisotropy: A Near-Perfect Pentagonal Bipyramidal Dysprosium(III) Single-Molecule Magnet

Cyclic (Alkyl)(Amino)Carbenes (CAACs): Stable Carbenes on the Rise

What Anions Do to N−H-Containing Receptors

Interaction of silver nitrate with readily identifiable groups: relationship to the antibacterialaction of silver ions

Preparation and Molecular and Electronic Structures of Iron(0) Dinitrogen and Silane Complexes and Their Application to Catalytic Hydrogenation and Hydrosilation

Formal S_N‐Type Reactions in Rhodium(III)‐Catalyzed CH Bond Activation

Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme

Facile Heterolytic Cleavage of Dihydrogen by Phosphines and Boranes

1.3‐Dipolare Cycloadditionen, XXXII. Kinetik der Additionen organischer Azide an CC‐Mehrfachbindungen

Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition to <i>N</i>-Activated Pyridines

Reinterpretation of the anomalous fluorescense of p-n,n-dimethylamino-benzonitrile

Methods and Mechanisms for Cross-Electrophile Coupling of Csp² Halides with Alkyl Electrophiles

Iron-Catalyzed Cross-Coupling Reactions

Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical

Preparation of Esters of Carboxylic and Phosphoric Acid<i>via</i>Quaternary Phosphonium Salts

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

Hydrogen sulfide mediates the vasoactivity of garlic

Nucleoside syntheses, XXII ¹⁾ Nucleoside synthesis with trimethylsilyl triflate and perchlorate as catalysts

Room-Temperature Palladium-Catalyzed Amination of Aryl Bromides and Chlorides and Extended Scope of Aromatic C−N Bond Formation with a Commercial Ligand

Selective, Nickel-Catalyzed Hydrogenolysis of Aryl Ethers

Benzo[<i>h</i>]quinolin-10-yl-<i>N</i>Iridium(III) Complexes

Im Goldenen Zeitalter der Organokatalyse

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

Ruthenium-Catalyzed Azide−Alkyne Cycloaddition: Scope and Mechanism

Über die quantitative Bestimmung von Lipoiden (Mikromethode) mittels der vielen natürlichen Lipoiden (allen bekannten Plasmalipoiden) gemeinsamen Sulfophosphovanillin-Reaktion

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

Über Madelungfaktoren

Hydroxyl radical scavenging activity of flavonoids

SCH 23390—The first selective dopamine D-1 antagonist

Pyridinium p-toluenesulfonate. A mild and efficient catalyst for the tetrahydropyranylation of alcohols

Transition metal complexes of semicarbazones and thiosemicarbazones

New complexes of ruthenium (II) and (III) with triphenylphosphine, triphenylarsine, trichlorostannate, pyridine and other ligands

Palladium-Catalyzed Methylation and Arylation of sp² and sp³ C−H Bonds in Simple Carboxylic Acids

Transition metal complexes of o-benzoquinone, o-semiquinone, and catecholate ligands

Construction of Pyridine Rings by Metal-Mediated [2 + 2 + 2] Cycloaddition

Quantitative analysis by various g.l.c. response-factor theories for partially methylated and partially ethylated alditol acetates

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

Cationic Gold(I) Complexes: Highly Efficient Catalysts for the Addition of Alcohols to Alkynes

Rh(III)-Catalyzed Directed C−H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile

Alkyl and aryl derivatives of π-cyclopentadienyl compounds of chromium, molybdenum, tungsten, and iron

Inhibition of Cancer Cell Growth by Ruthenium(II) Arene Complexes

KP1019, A New Redox‐Active Anticancer Agent – Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

Monoligated Palladium Species as Catalysts in Cross‐Coupling Reactions

Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols

Air Stable, Sterically Hindered Ferrocenyl Dialkylphosphines for Palladium-Catalyzed C−C, C−N, and C−O Bond-Forming Cross-Couplings

Effects of the interaction of tannins with Co-existing substances. VI. Effects of tannins and related polyphenols on superoxide anion radical, and on 1,1-diphenyl-2-picrylhydrazyl radical.

Strong Dimerization of Ureidopyrimidones via Quadruple Hydrogen Bonding

Regioselectivity of the borylation of alkanes and arenes

Hydrolytic Stability of Hydrazones and Oximes

Characterization of the first examples of isolable molecular hydrogen complexes, M(CO)3(PR3)2(H2) (M = molybdenum or tungsten; R = Cy or isopropyl). Evidence for a side-on bonded dihydrogen ligand

Heterocyclen aus CH‐aciden Nitrilen, VIII. 2‐Amino‐thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel

Synthetically Useful Reactions of Epoxides

Transition metal–carbon bonds. Part XLII. Complexes of nickel, palladium, platinum, rhodium and iridium with the tridentate ligand 2,6-bis[(di-t-butylphosphino)methyl]phenyl

Formation of CC Bonds by Addition of Free Radicals to Alkenes

Reactions of transition metal dihydrogen complexes

Indole Synthesis via Rhodium Catalyzed Oxidative Coupling of Acetanilides and Internal Alkynes

Chelation or Non‐Chelation Control in Addition Reactions of Chiral α‐ and β‐ Alkoxy Carbonyl Compounds [New Synthetic Methods (44)]

Heterocyclische Carbene – Synthese und Koordinationschemie

Palladium catalyzed synthesis of aryl, heterocyclic and vinylic acetylene derivatives

Guanidine and Amidine Organocatalysts for Ring-Opening Polymerization of Cyclic Esters

Palladium-Catalyzed Oxygenation of Unactivated sp³ C−H Bonds

Epoxidation of Lower Olefins with Hydrogen Peroxide and Titanium Silicalite

Oxygen radical chemistry of polyunsaturated fatty acids

An Efficient Waste-Free Oxidative Coupling via Regioselective C−H Bond Cleavage: Rh/Cu-Catalyzed Reaction of Benzoic Acids with Alkynes and Acrylates under Air

Frustrierte Lewis‐Paare: metallfreie Wasserstoffaktivierung und mehr

The use of new ionic liquids in two-phase catalytic hydrogenation reaction by rhodium complexes

Phosphine Organocatalysis

<i>N</i>-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: γ-Butyrolactones by Direct Annulations of Enals and Aldehydes

C−H···F Interactions in the Crystal Structures of Some Fluorobenzenes

Combined Effects on Selectivity in Fe-Catalyzed Methylene Oxidation

Stereochemistry of reaction paths at carbonyl centres

Inside Cover: Synergistic N‐Heterocyclic Carbene/Palladium‐Catalyzed Umpolung 1,4‐Addition of Aryl Iodides to Enals (Angew. Chem. Int. Ed. 1/2020)

A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides

Computational Study of the Mechanism of Cyclometalation by Palladium Acetate

Studies on the Mechanism of B(C₆F₅)₃-Catalyzed Hydrosilation of Carbonyl Functions

Methanolysis of Dimethyl (1-Diazo-2-oxopropyl) Phosphonate: Generation of Dimethyl (Diazomethyl) Phosphonate and Reaction with Carbonyl Compounds